LF:ZLIM051p Immunology - lecture - Course Information
ZLIM051p Immunology - lecture
Faculty of MedicineAutumn 2006
- Extent and Intensity
- 1/0/0. 2 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- prof. MUDr. Jiří Litzman, CSc. (lecturer)
prof. MUDr. Jindřich Lokaj, CSc. (lecturer)
prof. MUDr. Vojtěch Thon, Ph.D. (lecturer)
Miroslava Bučková (assistant) - Guaranteed by
- prof. MUDr. Jindřich Lokaj, CSc.
Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: prof. MUDr. Jiří Litzman, CSc. - Timetable
- Mon 6. 11. to Tue 2. 1. each working day 13:30–15:10 ÚKIA N01021
- Prerequisites (in Czech)
- ZLBC0221p Biochemistry I-lect. && ZLBI0222p Biology II-lecture && ZLBF011p Med.Physics and Informat.-lect && ZLFY0422c Physiology II - practice && ZLFY0422s Physiology II - seminar && ZLLM0421c Med.Microbiol.I-pract.
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Dentistry (programme LF, M-ZL)
- Syllabus
- Immunology in medicine.
- Anatomy and cellular elements of the immune system.
- Immune mechanisms. Innate and acquired immunity.
- Innate or natural immunity: phagocytosis, NK cells, cytotoxicity, interferon system, complement system, acute phase reaction, inflammation.
- B lymphocytes and immunoglobulins.
- Genetic basis of immunoglobulin heterogeneity.
- Biological properties of antibodies.
- Monoclonal antibodies as diagnostic and therapeutic tools.
- T-lymphocytes, their development and effector functions.
- Polarisation of T-lymphocytes (T1, T2). Cytotoxicity. Cytokines.
- Major histocompatibility complex: structure, function.
- Activation of T and B cells by antigen.
- Interactions between antigen-presenting cells and T- and B-lymphocytes.
- Regulation of the immune reaction.
- Mucosal immunity.
- Immunity against infection agents. Microbial antigens.
- Active and passive immunisation.
- Primary and secondary immunodeficiency disorders.
- HIV disease.
- Immunoglobulin therapy. Immunostimulation.
- Autoimmunity and disease. Immunological tolerance.
- Autoantibodies and their laboratory detection.
- Hypersensitivity reactions - anaphylactic, cytotoxic, immune complex, T-cell-mediated.
- Clinical allergology. Allergic skin and exposition tests.
- Ontogenesis of the immune system. Immunity in pregnancy. Reproduction immunology.
- Immunologic disorders in infants and children. Immunity in elderly.
- Tumor immunology. Tumor antigens. Immune response to tumors. Immunodiagnosis of tumors. Immune-related malignancies.
- Transfusion immunology. ABO system. Rh system. Transfusion reactions.
- Immunology of organ and bone marrow transplantation. Graft vs. host reaction.
- Literature
- HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 3. vyd. Praha: Triton, 2005, 279 s. ISBN 8072546864. info
- Abbas, Abul - Lichtman, Andrew. Basic Immunology. Philadelphia: Saunders, 2006. 336 s, ISBN: 1416029745
- BUC, Milan. Imunológia. 1. vyd. Bratislava: VEDA vydavateľstvo Slovenskej akadémie vied, 2001, 463 s. ISBN 8022406678. info
- Imunológia :základné termíny a definície. Edited by Miroslav Ferenčík - Jozef Rovenský - Štefan Nyulassy. 2. preprac. a dopl. vyd. Bratislava: Slovac Academic Press, 2001, 348 s. ISBN 80-88908-77-9. info
- FUČÍKOVÁ, Terezie. Základy klinické imunologie :imunodeficity - autoimunita - alergie. [1. vyd.]. Praha: RDI PRESS, 1994, 148 s. ISBN 80-900674-3-3. info
- Assessment methods (in Czech)
- Závěrečná ústní rigorózní zkouška
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- The course is taught annually.
- Listed among pre-requisites of other courses
- Enrolment Statistics (Autumn 2006, recent)
- Permalink: https://is.muni.cz/course/med/autumn2006/ZLIM051p