BLKKH0411p Clinical Haematology - lecture

Faculty of Medicine
Spring 2013
Extent and Intensity
0/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
RNDr. Ludmila Bourková (lecturer)
MUDr. Alena Buliková, Ph.D. (lecturer)
MUDr. Jarmila Kissová, Ph.D. (lecturer)
MUDr. Zdeněk Kořístek, Ph.D. (lecturer)
prof. MUDr. Miroslav Penka, CSc. (lecturer)
Mgr. Lucie Říhová, Ph.D. (lecturer)
MUDr. Petr Smejkal, Ph.D. (lecturer)
Michaela Gregorovičová (assistant)
Guaranteed by
prof. MUDr. Miroslav Penka, CSc.
Department of Internal Medicine, Hematology and Oncology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine
Contact Person: MUDr. Alena Buliková, Ph.D.
Supplier department: Department of Internal Medicine, Hematology and Oncology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine
Timetable
Fri 1. 3. 8:00–9:40 B11/327, 9:50–11:30 B11/327, Fri 19. 4. 8:00–10:30 B11/327
Prerequisites (in Czech)
BLKMB011p Mol.andCell.Biol.-lect.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This course includes information about the origin, development, structure and function of the system of hematopoietic cells and organs as well as of the blood clotting system. Both of them are described not only in health but also during various diseases inherited and acquired. Students will receive information summarizing pathophysiologic mechanisms, clinical and mainly laboratory findings in hematologic diseases and laboratory assays serving for treatment’s maintenance. The knowledge will allow students to interpret results obtained during hematological laboratory examination for diagnosis establishing and/or for differential diagnoses.
Syllabus
  • Origin and development of blood cells.
  • Basic principles of blood coagulation.
  • Plasmatic clotting factors, their physiology. Inherited bleeding disorders.
  • Primary hemostasis, platelet plug formation and its abnormalities.
  • Basic principles of anti-platelet therapy.
  • Inherited thrombophilias, anti-thrombotic treatment and its monitoring.
  • Acquired disorders of blood clotting.
  • Red cell disorders.
  • Myeloproliferative neoplasms.
  • Acute leukaemias.
  • Myelodyspastic syndrome.
  • Lymphoproliferative disorders.
  • Flow cytometry and molecular genetic assays for diagnosis of hematology diseases.
  • Therapeutic aphaeresis, basic principles of hemopoietic cells transplantation.
Literature
  • PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie krevní buňky. 1. vyd. Český Těšín: FINIDR, 2006, 304 s. ISBN 8086682021. info
  • PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie hemostázy. 1. vyd. Český Těšín: FINIDR, 2004, 237 s. ISBN 808668203X. info
  • PECKA, Miroslav. Přehled laboratorní hematologie. Bílá krevní řada, krevní destičky. [1. vyd.]. Praha: Galén, 1996, 132 s. ISBN 8085824434. info
  • Přehled laboratorní hematologie 1 :Krvetvorba. Červená krevní řada. Edited by Miroslav Pecka. [1. vyd.]. Praha: Galén, 1995, 141 s. ISBN 80-85824-28-0. info
Teaching methods
Students will attend two hours long lecture ones a week (14 per semester). Participation in lectures is optional. Each lecture is in the current version published on is.muni.cz.
Assessment methods
The course is closed by an examination which is divided into practical and an oral part. Practical part includes testing of haemostaseology or hematologic morphology, depending on the selected question. In the haemostaseology student performs basic coagulation test, interprets coagulation laboratory finding (four basic coagulation tests) and orally answers the selected question which is aimed at understanding the laboratory investigations in blood clotting. If the question is chosen from the morphological laboratory, the student evaluates 6 microscopic findings (in digital processing) and orally answers the selected question which is aimed at understanding the laboratory investigations in morphological diagnosis in haematology. In oral part student elects three questions, one of which is focused on non - oncological haematology, the second one concerns the blood coagulation and the third one at haematological oncology. Each question (one practical and three theoretical) is grades A-F. No grade F is necessary condition for passing an examination.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
General note: Všechny formy kontaktní výuky předmětu vyjma přednášek jsou povinné.Všechny formy kontaktní výuky předmětu vyjma přednášek jsou povinné.
Information on the extent and intensity of the course: 15 h/semestr.
The course is also listed under the following terms Spring 2011, Spring 2012, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020.
  • Enrolment Statistics (Spring 2013, recent)
  • Permalink: https://is.muni.cz/course/med/spring2013/BLKKH0411p