B7015 Chemical properties, structure and interactions of nucleic acids

Faculty of Science
Autumn 2000
Extent and Intensity
3/0/0. 3 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium), graded credit.
Teacher(s)
prof. RNDr. Emil Paleček, DrSc. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
Guaranteed by
prof. RNDr. Emil Paleček, DrSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Emil Paleček, DrSc.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 18 fields of study the course is directly associated with, display
Course objectives
Introduction. Nucleic acids - history. DNA double helix. Isolation and characterisation of nucleic acids. Physical properties of DNA and DNA conformation. Supercoil-stabilised local DNA structures. Nucleases, topoisomerases, helicases, ligases. Covalent interactions of Nas with small molecules. Reversible interactions of small molecules with DNA. Structure of RNA. Methods of nucleic acids analysis. Gene therapy. Oligonucleotides and their analogues. DNA-protein interactions. DNA structure and interactions in biomedicine. Protein p53 and its interactions with DNA.
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught every week.
The course is also listed under the following terms Autumn 2001.
  • Enrolment Statistics (Autumn 2000, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2000/B7015