C8858 Biocatalysis

Faculty of Science
Autumn 2007
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Zbyněk Prokop, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Zbyněk Prokop, Ph.D.
National Centre for Biomolecular Research – Faculty of Science
Timetable
Tue 10:00–11:50 C04/211
Prerequisites (in Czech)
- basic course of biochemistry and organic chemistry recommended - course of microbiology and molecular biology helpful
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives (in Czech)
Biocatalysis is the utilization of natural catalysts, called enzymes, to perform chemical transformations on organic compounds. Biocatalysis is multidisciplinary integration of emerging technologies from life sciences like bioinformatics, protein engineering (rational design and/or in vitro enzyme evolution), medium engineering and immobilization of the biocatalyst for optimum performance and recycling. Biocatalytical application covers the production of fine and bulk chemicals, pharmaceuticals and agrochemicals, environmental application, application in food industry as well as utilisation for analytical processes and diagnostics. The biocatalysis fulfills the concept of sustainable development with minimizing environmental impact (lowering waste production, energy and material consumption). The Biocatalysis course gives basic information about enzyme structure and function, clasification, production and purification of enzymes, enzyme engineering, development of biocatalytical industrial process and outlines the technical and economical potential of enzyme application, giving many examles of industrial processes using enzymes as biocatalyst.
Syllabus (in Czech)
  • 1. Opening Lecture 2. Introduction to Enzyme Technology 3. Basics of Enzymes as Biocatalysts 4. Kinetics of Enzyme Catalysed Reaction 5. Principles and Application of Enzyme Selectivity 6. Enzymes in Organic Synthesis I. 7. Enzymes in Organic Synthesis II. 8. Enzyme Production and Purification 9. Engineering of Biocatalysts 10. Immobilization of Enzymes and Cells 11. Reaction Engineering and Process Technology 12. Biotechnology Informatics
Literature
  • BUCHHOLZ, Klaus, Volker KASCHE and Uwe BORNSCHEUER. Biocatalysts and enzyme technology. Weinheim: Wiley-VCH, 2005, xvii, 448. ISBN 3527304975. info
  • FABER, Kurt. Biotransformations in organic chemistry : a textbook. 5th rev. and corr. ed. Berlin: Springer-Verlag, 2004, xi, 454. ISBN 3540200975. info
Language of instruction
English
Further Comments
The course is taught annually.
Teacher's information
http://loschmidt.chemi.muni.cz/peg/
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2006, Autumn 2008.
  • Enrolment Statistics (Autumn 2007, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2007/C8858