PřF:C7415 Structure and Reactivity - Course Information
C7415 Structure and Reactivity
Faculty of Scienceautumn 2017
- Extent and Intensity
- 0/1/0. 1 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
- Teacher(s)
- prof. RNDr. Petr Klán, Ph.D. (lecturer)
Mgr. Peter Štacko (seminar tutor) - Guaranteed by
- prof. RNDr. Petr Klán, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Petr Klán, Ph.D.
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science - Timetable
- Mon 18. 9. to Fri 15. 12. Mon 11:00–11:50 A08/309
- Prerequisites
- NOW( C7410 Structure and Reactivity )
organic chemistry, physical chemistry, physics - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Analytical Chemistry (programme PřF, D-CH) (2)
- Inorganic Chemistry (programme PřF, D-CH) (2)
- Physical Chemistry (programme PřF, D-CH) (2)
- Macromolecular Chemistry (programme PřF, D-CH) (2)
- Environmental Chemistry (programme PřF, D-CH) (2)
- Organic Chemistry (programme PřF, D-CH) (2)
- Organic Chemistry (programme PřF, M-CH)
- Organic Chemistry (programme PřF, N-CH)
- Course objectives
- The aim of this seminar is to practise the topics which were discussed in the course of Structure and Reactivity (C7410).
- Learning outcomes
- Students will be able to solve tasks from the field of structure and reactivity of organic molecules.
- Syllabus
- 1. Structure and reactivity relationship. Calibration points in chemistry. Inner parameters of the structure and its deformations. Physical properties caused by (a) geometry of nuclei, (b) electron density and its change. Activation and driving force of the chemical reactions. 2. Stability of molecules. Thermodynamic additive calculations. Conformations of acyclic and cyclic hydrocarbons. Heteroatom effects. Hyperconjugation. Anomeric effect. 3. Aromaticity a antiaromaticity. Aromatic ions and dipoles. Aromaticity of the transition state in the pericyclic reactions. 4. Non-covalent interactions and solvent effects. Solutions. Hughes-Ingold principles. H-bonding. Hydrophobic effect. Molecular recognition. 5. Proton transfer. Acid-base equilibria. 6. Chemical kinetics and reactivity. HSAB. Nucleophiles and electrophiles. Rate constants. Hammond and Curtin-Hammond principles. Driving force of the reactions. 7. Thermodynamics and kinetics - the tools to study chemical reactions. LFER. Hammett equation. Taft equation. QSAR. Kinetic isotope effects. Entropy vs. enthalpy. 8. Catalysis. Transition metal catalysis. Heterogeneous catalysis. Enzymatic catalysis. Brönsted catalysis. 9. Electron transfer. Marcus equation. 10. Photochemistry and photophysics. 11. Spin chemistry. Magnetic field effects. 12. Non-classical activation of chemical reactions.
- Literature
- ANSLYN, Eric V. and Dennis A. DOUGHERTY. Modern physical organic chemistry. Sausalito, Calif.: University Science Books, 2006, xxviii, 10. ISBN 1891389319. info
- Teaching methods
- Seminar - a calss discussion
- Assessment methods
- Attendance and working out of class assignment.
- Language of instruction
- Czech
- Follow-Up Courses
- Further Comments
- The course can also be completed outside the examination period.
The course is taught annually. - Listed among pre-requisites of other courses
- Enrolment Statistics (autumn 2017, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2017/C7415