Bi9001 Statistical analysis of biological data

Faculty of Science
Autumn 2023
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Milan Baláž, Ph.D. (lecturer)
Guaranteed by
RNDr. Milan Baláž, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Naděžda Bílá
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Thu 8:00–9:50 B09/316
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to familiarize the students with the logic of biological experiments - how the setup and design of these experiments must correspond with their aims, with the usage of appropriate statistical treatment of the data and with interpretation of results.
Learning outcomes
At the end of the course the students are able to:
 - set up experimental design suitable for specified purpose;
- select appropriate statistical treatment for the data and experimental design;
- calculate statistical test using the software Statistica;
- generalize and present the results of statistical tests using an adequate form.
Syllabus
  • Data collecting. Organization of data within spreadsheets. PC-based statistical packages. Data import from spreadsheets. Variable types, statistical distributions, quantiles, null hypothesis, I. and II. error type. Experimental design, selecting of appropriate statistical method. X2 test. F-test, t-test. One-way analysis of variance, homogeneity of variances, independence of residuals, data transformations, contrasts, a priori and post-hoc tests. Multiple analysis of variance: factorial, nested, and block designs, repeated measures ANOVA; interaction, fixed effect and random effect models, mixed model. Covariance analysis. Correlation analysis, Pearson, Spearman and partial correlation coefficient. Regression analysis, linear and non-linear regression, multiple regression.
Literature
  • LEPŠ, Jan. Biostatistika. Vyd. 1. České Budějovice: Jihočeská universita, 1996, 165 s. ISBN 8070401540. info
  • FRY, J. Biological data analysis - a practical approach. Oxford: Oxford University Press, 1994. info
  • SOKAL, Robert R. and James F. ROHLF. Biometry :the principles and practice of statistics in biological research. 3rd ed. New York: W.H. Freeman and Company, 1995, xix, 887 s. ISBN 0-7167-2411-1. info
Teaching methods
Lectures - theoretical preparation.
Assessment methods
The exam is based on the practical statistical treatment of three sets of experimental data, covering the methods presented at the course. Selection and justification of an method used is an integral part of the exam. For all calculations the package Statistica is used.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
General note: Předmět není určen studetům matematiky nebo matematické biologie - těmto bude jejich registrace/zápis anulován.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2024.
  • Enrolment Statistics (Autumn 2023, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2023/Bi9001