C6220 Clinical Biochemistry

Faculty of Science
Spring 2008 - for the purpose of the accreditation
Extent and Intensity
4/0/0. 4 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
prof. RNDr. Michaela Wimmerová, Ph.D. (lecturer)
RNDr. Petr Breinek (lecturer)
Guaranteed by
prof. RNDr. Michaela Wimmerová, Ph.D.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Michaela Wimmerová, Ph.D.
Prerequisites (in Czech)
C4182 Biochemistry II || C3580 Biochemistry || C5720 Biochemistry I
předpokládá se absolvování základní přednášky z biochemie a znalost základních metabolických drah na úrovni buňky.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 12 fields of study the course is directly associated with, display
Course objectives
The goal of this course is to provide general basic knowledge about biochemical and molecular aspects of pathobiological processes and use of biochemical tests to obtain diagnostic information. The course consisted from two part, pathobiochemistry and methods in clinical biochemistry. First part is designed to introduce the students to the theory and principles of (pato)biochemistry and (pato)physiology in health and diseases. Second part is focused to the theoretical background of clinical chemistry tests.
Syllabus
  • SECTION ONE: Laboratory techniques
  • Basic laboratory principles and calculations
  • Collection and handling of patient specimens
  • Methods in clinical biochemistry
  • Analysis of metabolites, proteins and enzymes
  • Automation
  • Laboratory statistics, reference values, quality control
  • Evaluation of methods
  • Section TWO: Pathobiochemistry
  • Body water and electrolytes
  • Renal function
  • Acid-base control and acid-base disorders
  • Liver function
  • Diabetes mellitus
  • Disorders of lipid and lipoprotein metabolism
  • Gastrointestinal function, pancreatic function, digestive disease
  • Bone disease
  • Biochemistry of muscle
  • Inborn errors of metabolism
  • Endocrine function
  • Tumor markers
Literature
  • ZIMA, Tomáš. Laboratorní diagnostika. 1. vyd. Praha: Galén, 2002, xxxii, 728. ISBN 8072622013. info
  • RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1st ed. Praha: Galén, 1999, 316 pp. ISBN 80-7262-023-1. info
  • Clinical biochemistry :metabolic and clinical aspects. Edited by S. K. Bangert - William J. Marshall. New York: Churchill Livingstone, 1995, xi, 854 s. ISBN 0-443-04341-8. info
  • MASOPUST, Jaroslav. Klinická biochemie. Požadování a hodnocení biochemických vyšetření. (Clinical chemistry.). 1st ed. Praha: Karolinum, 1998, 832 pp. část I. a část II. ISBN 80-7184-649-3. info
  • Clinical guide to laboratory tests. Edited by Norbert W. Tietz. 3rd ed. Philadelphia: W.B. Saunders Company, 1995, xxxix, 109. ISBN 0-7216-5035-X. info
  • KARLSON, Peter, Wolfgang GEROK and W. GROSS. Pathobiochemie. 1. vyd. Praha: Academia, 1987, 480 s. info
Assessment methods (in Czech)
ústní
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/michaw/teaching.htm
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021.