E2251 Risk Analysis - Practicals

Faculty of Science
Spring 2022
Extent and Intensity
0/1/0. 1 credit(s) (plus extra credits for completion). Type of Completion: z (credit).
Teacher(s)
doc. RNDr. Pavel Čupr, Ph.D. (lecturer)
Mgr. Ondřej Sáňka, Ph.D. (seminar tutor)
Mgr. Aneta Rafajová (seminar tutor)
Guaranteed by
doc. RNDr. Pavel Čupr, Ph.D.
RECETOX – Faculty of Science
Contact Person: doc. RNDr. Pavel Čupr, Ph.D.
Supplier department: RECETOX – Faculty of Science
Timetable
Thu 10:00–10:50 D29/347-RCX2
Prerequisites (in Czech)
NOW( E2250 Risk Analysis )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objective of this class/exercises is to acquire the practical experience and skills necessary for the planning, preparation and implementation of the whole process of assessment of health and environmental risks.
Learning outcomes
At the end of this course, students should be able to:
- practical use prospective and retrospective human and environmental risk assessment methods (windows PC)
- apply toxicokinetics of the main exposure routes (oral, inhalational, dermal, dietary exposure)
- solve a practical case studies with risk quantification from define exposure scenarios.
Syllabus
  • Introduction and selection of case studies (all students)
  • Practical PC calculations - examples: hazard identification, dose - response relationships, exposure analysis, risk characterization.
  • Toxicokinetic models, carcinogenic and non-carcinogenic risk assessment calculation – software applications.
  • Sensitivity analysis, Exposure Factor Handbook, probabilistic assessment - Monte Carlo approach.
  • New database sources (toxicology, effects, biomarkers; exposure parameters, intakes).
  • Ecological and environmental risk assessment - practical examples (equations).
  • Case study finalization (all students will have original study subject).
Literature
    recommended literature
  • FJELD, Robert A., Norman A. EISENBERG and Keith L. COMPTON. Quantitative environmental risk analysis for human health. Hoboken, N.J.: Wiley-Interscience, 2007, xiii, 390. ISBN 9780471722434. info
    not specified
  • WEB based data-bases (during exercises)
Teaching methods
A practical case study solution will be continuously carried out on a PC (SW, by each student). These Exercises will take place in a computer lecture-room. All students will have original case study subject.
Assessment methods
Knowledge will be evaluated by using of model examples calculated by students during the whole semester. Students must realize practical case study with risk quantification from define exposure scenarios (Individual Case Study).
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2022, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2022/E2251