Scientific Board of CEITEC MU
Meeting
10th November 2022
Overview of 2022
Jiří Nantl
Nature Index (NI)
2021 publications
Czech institutions Count
Number of results in NI
Share
Proportion of Local Authors According to the NI
Czech Academy of Sciences 470 91.36
Charles University 285 31.12
Masaryk University 92 16.04
Palacky University 113 15.49
University of Chemistry and Technology, Prague 32 10.15
Brno University of Technology 70 5.23
Czech Technical University in Prague 100 5.18
University of South Bohemia, Czech Republic 34 5.16
Mendel University in Brno, Czech Republic 61 4.64
Silesian University in Opava, Czech Republic 14 4.21
CEITEC MU 23 3.90
Publications 2022: Highlights
- Hluchy, M.; Gajduskova, P.; Ruiz de los Mozos, I.; Rajecky, M.; Kluge, M.; Berger, B.-T.; Slaba, Z.;
Potesil, D.; Weiss, E.; Ule, J.; Zdrahal, Z.; Knapp, S.; Paruch, K.; Friedel, C. C.; Blazek, D.
CDK11 Regulates Pre-MRNA Splicing by Phosphorylation OfSF3B1. Nature 2022, 609 (7928),
829-+. https://doi.org/10.1038/s41586-022-05204-z.
- Cairo, A.; Vargova, A.; Shukla, N.; Capitao, C.; Mikulkova, P.; Valuchova, S.; Pecinkova, J.;
Bulankova, P.; Riha, K. Meiotic Exit in Arabidopsis Is Driven by P-Body–Mediated Inhibition of
Translation. Science 2022, 377 (6606), 629–634. https://doi.org/10.1126/science.abo0904.
- Zapletal, D.; Taborska, E.; Pasulka, J.; Malik, R.; Kubicek, K.; Zanova, M.; Much, C.; Sebesta, M.;
Buccheri, V.; Horvat, F.; Jenickova, I.; Prochazkova, M.; Prochazka, J.; Pinkas, M.; Novacek, J.;
Joseph, D. F.; Sedlacek, R.; Bernecky, C.; O’Carroll, D.; Stefl, R.; Svoboda, P. Structural and
Functional Basis of Mammalian MicroRNA Biogenesis by Dicer. Molecular Cell 2022, 82 (21),
4064-4079.e13. https://doi.org/10.1016/j.molcel.2022.10.010.
Research Field - Oriented Analysis
Quality of CEITEC MU Publications in Subject Categories: Percentage of
Publications in Q1 in 2021
63%
19%
93%
30%
40% 38%
33%
93%
54%
14%
45%
56%
22%
67%
31%
100%
30% 33%
45%
57%
86%
57%
40%
67%
33%
25%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
PercentageofQ1publications
CEITEC MU publications in 2021 CEITEC MU publications with corresponding authorship in 2021
National evaluation system „M17+“
Module 1: Quality of Selected Results
Evaluations of nebiblio results
(summary of evaluation H17 – H21)
Evaluations of biblio results
(evaluation H19 - H21)
1 1 4
7
11
27
11
20
42
4 14 19
2 2
12
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
CEITEC MU LF PřF
world-leading excellent very good
average below -average
17
10
15
22
17
59
1 2
24
1 1
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
CEITEC LF PřF
world-leading excellent very good average
Grants
The grant strategy is based on individual research grants.
CEITEC MU has a higher than national average success rate in all
national grant schemes.
CEITEC has ambition to receive institutional grants that support further
development initiatives at a larger scale: Horizon Europe – Teaming and OP
JAK.
Success rate in % of projects submitted and awarded
Percentage Success Rate – Submitted / Awarded Projects
2018 2019 2020 2021
National 43% 23,90% 31,80% 32,70%
International 12,80% 32% 30,80% 30,30%
CEITEC wants to strengthen Brno´s position on the global electron microscopy map
TEAMING proposal submitted
- CORMIC - Bridging Academia and Industry in Correlative Microscopy
- Partners: CEITEC MU, CEITEC BUT, ISI CAS, EMBL, TU-Wien
- Impact
- life science research leveraging correlative microscopy approaches
- microscopy technology development at the interface of life and material sciences
- education of experts in microscopy
- technology transfer and entrepreneurial spirit
- Submission 2nd round: 8th September 2022
- Evaluation result expected: December 2022
- Competition:
- 116 proposals to 1st round evaluation (9 from the Czech Republic submitted)
- 32 projects were invited for 2nd round, max. 10 projects will be awarded
Selected Grant Achievements 2022
- P. Plevka: ERC Consolidator – EU - Phage infection of bacterial biofilm (1 992 976 EUR)
- J. Hritz: Excellence Hubs – Horizon Europe - Alzheimer's Disease Diagnostics Innovation
and Translation to Clinical Practice in Central Europe (1 684 319 EUR)
- I. Rektor: Pathfinder - EIC - First Closed-loop non-Invasive Seizure Prevention System
(356 500 EUR)
- A. Ghosh (RG L. Trantírek): MSCA-PF – Horizon Europe - In vitro and In-cell
characterization of Quadruplex-duplex hybrids: conformation, folding, ligand binding and
implications for in-cell NMR based assays (166 279 EUR)
- P. Plevka: EXCELES – National Recovery Plan (MEYS) – National Institute of Virology
and Bacteriology (7 mil. EUR)
- O. Slabý: EXCELES – National Recovery Plan (MEYS) - National Institute for Cancer
research (2,4 mil. EUR)
TWO GA CR EXPRO for CEITEC MU
- K. Říha: GAČR EXPRO - Biomolecular condensates in plant germline differentiation (49 730 000
Kč)
- D. Blažek: GAČR EXPRO - Identification and characterization of a new pathway regulating premRNA
splicing (49 981 000 Kč)
GA CR Project
Proposals 2023
(total/awarded)
CEITEC ECON PHARM ARTS FI SPORT FSS MED PED LAW SCI ICS TOTAL
EXPRO 6/2 0 0 3/0 0 1/0 3/1 0 0 0 2/0 0 15/3
JUNIOR STAR 2/0 3/0 1/0 3/1 1/0 2/0 2/0 0 0 0 4/1 1/0 19/2
TOTAL SUM 8/2 3/0 1/0 6/1 1/0 3/0 5/1 0 0 0 6/1 1/0 34/5
GA CR
EXPRO 2020 2021 2022* 2023
Submitted Projects GA CR- (MU*) 133 (24) 123 (24) - ? (15)
Awarded Projects GA CR- (MU*) 22 (3) 16 (6) - 10 (3)
Success Rate in % - CR TOTAL (MU*) 16,5 (12,5) 13 (25) - ? (20)
JUNIOR STAR 2021 2022 2023
Submitted Projects GA CR- (MU*) 355 (28) 315 (28) ? (19)
Awarded Projects GA CR- (MU*) 30 (2) 16 (3) 23 (2)
Success Rate in %- CR TOTAL (MU*) 8,4 (7,1) 5 (10,7) ? (10,5)
CEITEC PhD School
- Currently 79 students in total
- Gender balance: 41F / 38M
- 38 international students from
17 countries
- Graduates 7 (2021 – 3 graduates)
- Abandoned studies: 1
Life Sciences Programme (Sci)
- newly re-accredited since
the academic year 2021/2022
- students 75 / international 52
Molecular Medicine (Med)
- first international students (3)
admitted in 2021
- students 6 / international 3
Community
events
Scientific
events
Public
events
Retreats
Group leaders
Postdocs
PhDs
Career
development
events
Events as a building blocks of community development
- EMBO Course Light sheet microscopy
- Leadership and Mentoring Skills for Research Group Leaders and
Core Facility Heads by Saša Kočevar, Thomas Frick
- SIY Adaptive Resilience Series – Mental Health and Stress
Management for postdocs
- How to be an Active Bystander by Magali Berger Churchill
- Presentation skills for Research Group and Core Facility Heads by
Dr Samuel Lagier
- Communication in media by Czech Press Office
- Culture Differences in Communication by Eva Gaborikova
15
Selected training
Awards for CEITEC
researchers in 2022
- Rector's Award for
Extraordinary International
Grant Competition Results –
Robert Vácha
- Rector's Award for
Outstanding Research
Results Achieved by Young
Scientists under 35 –
Zdeněk Farka
- Rector's Award for
innovations in teaching –
Nikola Kostlánová
- NEURON Prize for promising
scientists – Gabriel Demo
- Purkyne Foundation Award
for best publication –
Václav Šeda
- New EMBO member –
Šárka Pospíšilová
TECHNOLOGY TRANSFER: Successful
Cases 2022
- Licence:
- licence agreement with AI|ffinity to use softwares:
- 4D CHAINS: 30kCZK/year + 8% royalties
- 4D GRAPHS: 40kCZK (one-time fee) + 8% royalties
- Service Agreements:
- ECM DIAGNOSTICS (RG Ondřej Slabý, 5kUSD)
- BioVendor (CF Genomics, 36kCZK)
- Collaboration Agreement:
- AppsDevTeam (CF Bioinformatics/RG Panagiotis Alexiou)
- Amendment to Collaboration Agreement (contract extension):
- Thermo Fisher Scientific (CF CryoEM)
Applied Results 2020-2022*
Scientific Board 2022
Legend:
P – Patent (granted), Pa – Patent application, F – Utility Model, G – Prototype, N – Methodics, R – Software, Z – Pilot Plant
*period 1.1.2020 – 4.11.2022
Dissolution of Panagiotis Alexiou
Research Group
Congratulation to
Panagiotis Alexiou
who have been offered
and accepted an ERA
Chair position to build
up a Bioinformatics
research program at
the University of Malta.
ISAB 2022
ISAB 2022
Dorothea Bartels
Claudia Köhler
Gaia Pigino
Witold Filipowicz Michal Hocek
Philipp SelenkoJohannes Zuber
Christoph M. MichelDirk Inzé
Viktor K. Jirsa
Michael Hothorn
Eric Lecuyer
Evaluation of research excellence 2022
Evaluation of research
excellence 2022
- Mini-conference: 17. 10. 2022
- Interviews: 18. 10. 2022
- Meeting with CEITEC MU
management: 19. 10. 2022
- Final report expected in November
CEITEC MU
Core Facilities
Pavel Plevka
Chair: Pavel Plevka, CEITEC MU Deputy
Director for Research Infrastructure
Members:
- Karel Říha, CEITEC MU Deputy Director
for Science
- Martin Blackledge, Institut de Biologie
Structurale
- Fernando Peláez, CNIO
- Jakub Jež, Vienna BioCenter Core
Facilities (VBCF)
- Claus Lamm, University of Vienna
- Gábor Csúcs, ETH Zürich
Secretary: Kateřina Hošková, CEITEC MU Core
Facilities and Research Infrastructure Specialist
On-site support: Pavla Pospíšilová, CEITEC MU
project administrator
2022 CF Evaluation
Acknowledgments to CFs
Number of users
Internal vs. external users
CF day 22. 11. 2022
- Event webpage:
bit.ly/CFDayMeeting2022
- Hybrid: ZOOM / E35-145
- Content:
- CF overview – services, trainings,
user rules
- New instrumentation
- CF data policy
09:45 – 10:00 waiting room/technical preparedness
10:00 – 10:10 CF introduction - Ester Jarour
10:10 – 10:30 CF Plants
10:30 – 10:50 CF NMR
10:50 – 11:00 coffee break
11:00 – 11:20 CF Nanobiotechnology
11:20 – 11:40 CF CryoEM
11:40 – 12:10 CF BIC + X-ray
12:10 – 13:00 Lunch break
13:00 – 13:20 CF Proteomics
13:20 – 13:40 CF CELLIM
13:40 – 14:00 CF MAFIL
14:00 – 14:10 coffee break
14:10 – 14:30 CF Genomics
14:30 – 14:50 CF BioIT
14:50 – 15:10 CF BioData
15:10 – 16:00 discussion room
Long term vision + strategy
- Anticipate developments in research methods:
- Promote integrative services – analyses of samples by multiple CFs.
- Reflect in future purchases of instruments.
- Expand support provided to users in data analyses.
- Strategy to handle increased amounts of recorded data & open data –
BioData CF.
- Strategy to maintain / discontinue depreciated but useful instruments (risk
management).
- HR strategy of CF focused on staff retainment and development/training.
- Implementation of electronic tools for data management and
communication with users.
Radovan Fiala Zbyněk Zdráhal
Jaromír MarekJosef Houser
Jiří Nováček
Jan Přibyl
Michal Mikl Markéta Pernisová Boris Tichý
Milan Ešner Panagiotis Alexiou Radka Svobodová
Acknowledgments(1):
CF administration team
Kateřina Hošková
Core Facilities and
Research Infrastructure
Specialist
Radka Kejmarová
Administrator -
monitoring,
reporting, internal
invoicing
Pavla Pospíšílova
Administrator external
invoicing
Daria Kuchařová
Project manager - Horizon
projects
Tomáš Bártek
Booking system
administration,
technical support
Acknowledgments(2):
• RI support is major source of
financing of CEITEC CFs.
• Current project scheme ends
12/2022.
• New projects for the period
2023-2026 are expected to
be reduced to 75-50% of the
requested budget
• CFs participate in 15
national and 8 international
projects
• In 2020 – 2021, almost 300 million CZK / 11.3 million EUR was invested in new technologies and instrument
upgrades thanks to OP VVV projects
Operation costs 3.3 million EUR in 2021
Thank you for your attention
- In the case of questions, contact us at: core.facilities@ceitec.muni.cz
- Follow the webpage: https://www.ceitec.eu/core-facilities/
CEITEC
@CEITEC_Brno
General debate