Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Pathologic anatomy (introductory lecture) September 16, 2007 Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Pathologic anatomy Institute of pathology medical practice (biopsy, autopsies) teaching research Department of pathology in smaller hospitals (medical practice) Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Pathology, morphology Deals with morphologic characteristics of diseases. According to morphologic features pathologists classify and define diagnostic units (diseases). Other methods and features are used to classify the diseases today: microbiology, immunohistology, molecular genetics. . . ). The ultimate goal of classifications is to define diagnostics units according to reliable criteria. This classifications must correlate with clinical features of the disease (prognosis, reaction to therapy. . . ). Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy General and organ pathology General pathology Organ pathology Deals with diseases and their progress in different organ systems Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy General and organ pathology General pathology Organ pathology Studies individual organs or organ systems and their diseases Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Pathology and its position in medicine standalone scientific discipline part of clinical medicine Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Pathology and its position in medicine standalone scientific discipline part of clinical medicine autopsy verifies correctness of diagnosis and therapy biopsy necessary to make a diagnosis, progress and extent of a disease and sometimes to verify the therapy Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Recommended literature Books Basic Pathology (Kumar, Cotran, Robbins) General and Systematic Pathology (Underwood) Pathology, Basic and Systemic (Woolf) Internet Hypertext atlas of pathology (in Czech) Hypertext atlas of dermatopathology Hypertext atlas of fetopathology Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Institutes of Pathology in Brno till 1962: Institute of Pathology, St. Anna Hospital 1981 – 1983: bioptic department of MOÚ 1992 – 1995: bioptic department in Bohuice 1994: private pathology Biocyt Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Institutes of Pathology in Brno till 1962: Institute of Pathology, St. Anna Hospital 1981 – 1983: bioptic department of MOÚ 1992 – 1995: bioptic department in Bohuice 1994: private pathology Biocyt Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Institutes of Pathology in Brno till 1962: Institute of Pathology, St. Anna Hospital 1981 – 1983: bioptic department of MOÚ 1992 – 1995: bioptic department in Bohuice 1994: private pathology Biocyt Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Institutes of Pathology in Brno till 1962: Institute of Pathology, St. Anna Hospital 1981 – 1983: bioptic department of MOÚ 1992 – 1995: bioptic department in Bohuice 1994: private pathology Biocyt Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy 1st institute of pathology Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy (2nd) Institute of pathology Brno Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy prof. Sternberg Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy prof. Neumann Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy prof. Švejda Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy prof. Dluhoš Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Examinations performed by pathologists Autopsy Biopsy (surgical pathology) pathological (medical reasons) forensic Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Examinations performed by pathologists Autopsy Biopsy (surgical pathology) Biopsy (tissues) Cytology Special methods of genetic analysis Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy The course of the autopsy External examination of a body Organ removal Autopsy of the organs, description, taking samples Putting the organs back, preparation for funeral Administrative tasks; autopsy protocol Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy The course of the autopsy External examination of a body Organ removal Autopsy of the organs, description, taking samples Putting the organs back, preparation for funeral Administrative tasks; autopsy protocol Performed by laboratory assistent. Organ complexes are removed from the body. It is important not to damage the body over the necessary minimum; sections can be covered by clothes. Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy The course of the autopsy External examination of a body Organ removal Autopsy of the organs, description, taking samples Putting the organs back, preparation for funeral Administrative tasks; autopsy protocol Autopsy of the organs is usually performed by standard method. Parts of dissected organs are opened in the same way, which enables to compare the findings. Specimens of tissues are taken for microscopic examination and other specimens are taken for microbiology and other methods. Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy The course of the autopsy External examination of a body Organ removal Autopsy of the organs, description, taking samples Putting the organs back, preparation for funeral Administrative tasks; autopsy protocol The body is prepared for the funeral. Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy The course of the autopsy External examination of a body Organ removal Autopsy of the organs, description, taking samples Putting the organs back, preparation for funeral Administrative tasks; autopsy protocol Autopsy protocol is put together by pathologist after the autopsy is performed and results of other examinations are available. Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Cooling boxes Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Autopsy protocol Description of the autopsy and macroscopic changes Evaluation of histological findings and results of other examinations Diagnostic conclusion Epicrisis (concise) Correlation of the clinical and pathological findings External changes, organ changes, organ weights Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Autopsy protocol Description of the autopsy and macroscopic changes Evaluation of histological findings and results of other examinations Diagnostic conclusion Epicrisis (concise) Correlation of the clinical and pathological findings Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Autopsy protocol Description of the autopsy and macroscopic changes Evaluation of histological findings and results of other examinations Diagnostic conclusion Epicrisis (concise) Correlation of the clinical and pathological findings 1. Basic disease (morbus principalis) 2. Complications (complicationes) 3. Cause of death (causa mortis) 4. Accessory findings (inventu accessorii) Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Autopsy protocol Description of the autopsy and macroscopic changes Evaluation of histological findings and results of other examinations Diagnostic conclusion Epicrisis (concise) Correlation of the clinical and pathological findings In one or two sentences to summarize the basic disease, its course and the cause of death. Patologic anatomy Pathologic anatomy Morphologic pathology General and organ pathology Pathology and its position in medicine Recommended literature Institutes of Pathology in Brno 1st institute of pathology 2nd institute of pathology Historie Methods of pathology Autopsy Autopsy protocol Description of the autopsy and macroscopic changes Evaluation of histological findings and results of other examinations Diagnostic conclusion Epicrisis (concise) Correlation of the clinical and pathological findings 1. full correlation of clinical and autoptic findings 2. small differences 3. substantial differences, when the clinical diagnosis is incomplete or partially wrong and such incorrect diagnosis influenced the therapy 4. complete discrepancy between the clinical and autoptical finding