1) Tomas Otahal

Corruption in economic theory

The thesis’ aim [SB1] is to explain the corruption problem from the perspective of two different
economic theories and to provide the [SB2] theoretical solution suitable for both explained
theories. In the methodological part[SB3] , it is argued why the argumentation [SB4] is built on
the principle of methodological individualism followed by deductive analysis supported with
evidence from [DEL: the :DEL] historical examples. Corruption is introduced through [DEL: the :DEL]
[INS: an :INS] example of bribery.

In the [SB5] theoretical part, the author explains the historical evolution of agency theory and
rent-seeking. The author explains how both the agency theory and rent-seeking understand the
problem of corruption and the problems of suggested public policies deduced from both theories. It
is argued that while [DEL: the :DEL] agency theory lacks the concrete explanation of institutional
environment within which corruption [DEL: problem :DEL] occurs, rent-seeking[DEL: s :DEL] lacks the
positive definition of rules [INS: which :INS] determin[INS: e :INS] [DEL: ing :DEL] how corruption
should be [INS: addressed/eliminated :INS] [DEL: solved :DEL] .

In the analytical part[SB6] , the author suggests [DEL: the :DEL] [INS: a :INS] theoretical
framework [INS: which :INS] connect[INS: s :INS] [DEL: ing :DEL] both the agency theory and
rent-seeking together. The author explains that the suggested theoretical framework applied on
historical examples implies that [SB7] the system[INS: s :INS] [DEL: of :DEL] [INS: for the :INS]
creation of legal rules and [DEL: the system of :DEL] their enforcement are crucial for [INS:
offering :INS] solution[INS: s :INS] [DEL: of :DEL] [INS: to :INS] [INS: problems with :INS]
corruption [DEL: problem :DEL] in every society. More precisely, it is argued that when the system
[DEL: of :DEL] [INS: for the :INS] creation of legal rules is subordinated to the citizens’ control
and the independent judicial system is subject to competition, the problem of corruption is not so
preva[DEL: i :DEL] l[INS: ent :INS] [DEL: ing :DEL] [INS: when :INS] compared with dictatorial
states. [INS: The :INS] [DEL: C :DEL] [INS: c :INS] onclusion [INS: presents a :INS] summar[INS: y
:INS] [DEL: izes :DEL] and provides explicit explanation[INS: s :INS] of [INS: the :INS] author’s
contribution[INS: [to…?] :INS] .

2) Jiri Palicka

Although the [SB8] gene therapy [INS: has :INS] achieved undeniable clinical successes[INS: [when
and where?] :INS] , its use for cancer treatment is still limited [DEL: by :DEL] [INS: due to :INS]
the low efficiency of gene transfer. One of the possibilities to achieve higher number of affected
cancer cells [SB9] is intercellular spread of the transgene product. Using the known signal
sequences responsible for [INS: the :INS] inter- and intracellular trafficing of proteins is [INS:
[unclear from this point onwards...] :INS] the transgene engineered to make its product, the
produced protein, capable of being secreted from the affected cells and taken up by the neighboring
cells. [INS: :INS]

[INS: The :INS] [DEL: A :DEL] [INS: a :INS] im of this diploma [INS: [usually, the diploma/BSc/MSc
etc is not mentioned here] :INS] thesis [DEL: wa :DEL] [INS: i :INS] s to improve cellular uptake
of the transgene product. The gene for Cre recombinase and the cell line containing reporter
cassette allowing detection of presence of the Cre recombinase in a cell nucleus was chosen as a
reporter system. Within this project, [INS: a :INS] method of bacterial expression and purification
of an enzymatically active Cre-fusion protein was established and its capability of entering the
reporter cells was [INS: then :INS] assessed. Furthermore, transgenes containing additional protein
transduction domain TAT from the HIV virus and an endosomal escape signal from the Influenza virus
were constructed. Their activity was not examined [DEL: in the :DEL] [INS: due to :INS] limited
time[INS: /time limitations :INS] .

3) Sarka Masova

"Morphometric and molecular characterization of Multicaecum heterotis (Nematoda: Heterocheilidae)
from Heterotis niloticus (Osteoglossiformes) with determination Key of Multicaecum and
Brevimulticaecum species"

Ascaridoid nematode species Brevimulticaecum heterotis (Petter, Vassiliadès et Marchand, 1979)
Khalil, 1984 [SB10] were recorded from the intestine of the African bonytongue, Heterotis niloticus
(Cuvier) [SB11] (Arapaimidae, Osteoglossiformes) from the Mare Simenti in the Niokolo Koba National
Park, East Senegal and from Kosti, Sudan. [INS: [< this first sentence is somewhat long and
difficult to follow] :INS] Th[INS: is :INS] [DEL: e :DEL] study includes[INS: a focus on
the/reference to the :INS] morphometrical and molecular approaches [INS: required for the :INS]
[DEL: to :DEL] identification of the nematode parasite B. heterotis. Specimens were examined and
redescribed based on light and, for the first time, environmental scanning electron microscopy
(ESEM) and SEM[SB12] . These methods revealed some findings of [SB13] morphological features such
as dentigerous ridge with small sharp denticles on the upper edge of [INS: the :INS] lip. On the
basis of this feature this taxon belongs back to genus Multicaecum Baylis, 1923. B. heterotis
differs from [INS: the :INS] generic diagnos[INS: is :INS] [DEL: e :DEL] of Brevimulticaecum
Mozgovoy in Skrjabin, Shikhobalova et Mozgovoy, 1951 mainly by presence of dentigerous ridges on
lips, location of excretory pore at level or behind nerve ring, vulva location in front half of the
body. The study [INS: also :INS] contains [INS: a :INS] [DEL: also a :DEL] key for [INS: the :INS]
determination of species from genus Multicaecum and Brevimulticaecum, and the first published
sequence of species from the genus Multicaecum.[INS: :INS]

[INS: [The referencing is unclear and this causes confusion and a lack of clarity between :INS]
[INS: a citation and a technical term] :INS]

4) Khomaini Hasan

Mycobacterium tuberculosis H37Rv HALOALKANE DEHALOGENASE (DmbC): BIOCHEMICAL, SUBSTRATE
SPECIFICITY, AND STRUCTURAL CHARACTERIZATIONS

Haloalkane dehalogenases (EC. 3.8.1.5) are enzymes which catalyze the hydrolytic conversion of
various halogenated compounds to [INS: a :INS] corresponding alcohol and halide ion. Because of its
broad substrate specificity, haloalkane dehalogenases are promising biocatalysts for
bioremediation, biocatalysis, and biosensing. Herein, we report [INS: on the :INS] haloalkane
dehalogenases DmbC from Mycobacterium tuberculosis H37Rv which demonstrate dehalogenase activity of
their translational products. [INS: :INS]

DmbC was produced in recently developed Mycobacterium smegmatis expression host system. [DEL: DmbC
:DEL] [INS: It :INS] was purified to homogeneity by nickel affinity chromatography and its
characteristics have been investigated covering biochemical, substrate specificities, and secondary
structure. DmbC exhibited lower catalytic activity with 30 tested halogenated substrates, but novel
specificity towards iodinated and brominated aliphatic compounds. [INS: The optimum temperature of
the :INS] DmbC [DEL: has temperature and optimum at :DEL] [INS: is :INS] 40 Celcius degree[INS: ,
:INS] and pH optima at 8.3[INS: , :INS] by using 1,3-diiodobutane as a substrate. Secondary
structure of DmbC measured by means of circular dichroism spectroscopy revealed that DmbC is
constructed by alpha/beta-hydrolase family-like structure. Even though the size of 32.9 kDa
monomeric unit of DmbC estimated by SDS PAGE is analogous to other known haloalkane dehalogenases,
this enzyme is unique by forming large homo-oligomeric units. Oligomeric state characteristic of
DmbC was confirmed by gel filtration, dynamic and static light scattering. Furthermore, [INS: the
:INS] presence of detergents in purification buffers in reaction mixture of DmbC showed [INS: a
:INS] clear effect on protein activity. [INS: The :INS] [DEL: A :DEL] [INS: a :INS] ddition of
[INS: the :INS] detergent Tween 80 and DMSO to the protein sample of DmbC results in [INS: the
:INS] formation of [INS: a :INS] lower oligomeric state and [INS: a :INS] higher catalytic
activity.

5) Dana Smerdova

The importance, advantages and dificulties in using elements of method Video interaction guidance
(VIG) in preparation student teachers[SB14]

The contribution [SB15] deals with [SB16] the research which has being realised within di[INS: s
:INS] sertation aims to express importance, posibilities and dificulties in the implementation
elements of method Video interaction guidance in preparation students of education, so future
teachers, in the Faculty of Education. [DEL: It set itsef a :DEL] [INS: The :INS] task [INS: is
:INS] to outline and highlight close interconnecti[INS: ve :INS] [DEL: on of :DEL] [DEL: the :DEL]
links of the communication and interaction at school for the development abilities and [INS: the
:INS] skills[INS: that :INS] future teachers intentionally create positive psychosocial climate at
school as the important precondition meaningful and effective teaching, where teachers are able to
change bad conditions of teaching to be more in tune with human nature and basic human needs, the
both - pupils and also teachers[SB17] . Further[INS: , :INS] it presents partial findings in
students teachers [SB18] conception [SB19] of the educational communication and interaction and
ability students teachers to interpret interaction in the clasrooms between teachers and pupils
which are alarming in some way but understandable in the [DEL: k :DEL] [INS: c :INS] ontext, and
then describes [DEL: a :DEL] reasons and advantages for using of elements[INS: of :INS] VIG in
students teachers preparation.

6) Zuzana Petrovicova

"Taking Responsibility in Adolescence and its Relationship to Parenting Style"

The aim of [INS: this :INS] [DEL: present :DEL] study [DEL: wa :DEL] [INS: i :INS] s to examine the
relationship between components of responsibility-taking among adolescents and [INS: its
correlation with the :INS] perceived parenting[DEL: :DEL] [INS:   :INS] style and enabling.
[SB20] [INS: The :INS] [DEL: P :DEL] [INS: p :INS] articipants [INS: for this study :INS] were 140
middle (14-16 years of age) and late (16-18 years of age) adolescents and their parents from a
midsize town in western Slovakia. Students were [DEL: equally :DEL] divided [INS: equally :INS] by
age and gender. [INS: The :INS] [DEL: A :DEL] [INS: a :INS] dolescents[INS: /participants :INS]
completed self–report measures of identity (translated EOMEOS-2), attributional style (shorten
version of ASQ), personal and family responsibilities, and well established measure of parenting
style. [INS: The :INS] [DEL: P :DEL] [INS: p :INS] arents filled in [INS: a :INS] parenting style
questionnaire and [INS: an :INS] enabling survey[INS: . :INS] [DEL: for parents :DEL] .

Correlations and multiple hierarchical regressions were computed. Significant positive correlations
were found between parental enabling and autonomy granting (r=.50, p<.01for mothers, r=.43, p<.01
for fathers), and between non-enabling and demandingness [SB21] (r=.49, p<.01 for mothers). [DEL:
The :DEL] [INS: A :INS] relationship [INS: was found :INS] between personal responsibilities and
paternal positive emotions[DEL: was found :DEL] , while family[DEL: :DEL] [INS: - :INS] related
responsibilities were [DEL: related :DEL] [INS: attributed :INS] to maternal[INS: :INS] [DEL:
:DEL] [DEL: positive :DEL] emotions. Hierarchical regression revealed that internality was best
predicted by parental demandingness and non-enabling. For the purposes of our study, we calculated
[INS: an :INS] exploration and commitment score and regressed them on components of parenting,
enabling, and dimension of attributional style. Exploration was best predicted by maternal negative
emotions (β=-.36, p<.01), paternal demandingness (β=.29, p<.01), and stability (β=.24, p<.05).
Commitment was best predicted by maternal negative emotions (β= -.45, p<.01), accounting for 26% of
variance.

The study found a relationship between the autonomy component of parenting and parental
enabling[INS: ; :INS] [DEL: , :DEL] both [INS: were :INS] negatively related to internality. [DEL:
The :DEL] [INS: A :INS] relationship between identity statuses and components of parenting were
also found, supporting the existing theories. Implications for [DEL: the :DEL] future research will
[INS: also :INS] be discussed[INS: in this paper :INS] .

7) Jana Supikova

FOCUSED MICROARRAY FOR LYMPHOMA DIAGNOSTICS

Background

Non-Hodgkin [DEL: l :DEL] [INS: L :INS] ymphomas (NHL) represent a heterogeneous group of
lymphoproliferative disorders with highly variable clinical course and outcome. In some cases,
current diagnostic methods based on histopathology and immunohistochemistry may be insufficient for
exact tumor classification and subjectively influenced by pathologist[DEL: ’s :DEL] experience[INS:
s :INS] , especially in Burkitt’s lymphoma. [DEL: Neither p :DEL] [INS: P :INS] rognostic markers
such as the International Prognostic Index (IPI), although highly useful, do not capture all the
variability that affects [INS: the :INS] clinical behaviour of lymphomas. The genome-wide
transcriptional profiling was reported to accurately define the biological phenotype of the tumor.

Aims

The aim of the project was to design novel focused oligonucleotide microarray directed at molecular
diagnostics and prognostication of lymphoproliferative disorders, particularly non-Hodgkin
lymphomas, and to test its reliability on a cohort of newly diagnosed lymphoma samples.

Methods

We [SB22] designed custom oligonucleotide microarray (Agilent 8x15K custom array) carrying specific
probes for approximately 4000 genes. The genes represented on the microarray were selected on the
basis of previously published lymphoma/leukemia gene expression profiling studies. In addition,
probes for the genes implicated in crucial cellular processes such as apoptosis or cell cycle
control were added. To provide more information, the genes for the majority of CD antigens and
„housekeeping“ genes were also included in the microarray design.

67 histologically characterised samples were analysed – 18 Diffuse Large B-cell Lymphomas (DLBCL),
34 Follicular Lymphomas (FL), 3 Burkitt’s Lymphomas (BL), 1 MALT Lymphoma, 6 non-malignant
lymph-nodes and 3 lymphoma cell lines (SU-DHL-4, WSU-NHL, RAMOS). RNA was obtained either from
fresh-frozen lymph-node resections, or from RNA[INS:   :INS] later preserved needle biopsy samples.

Summary

We demonstrated the benefit of gene expression profiling using [INS: a :INS] novel designed focused
microarray for non-Hodgkin lymphoma characterisation. The technology is robust, [DEL: less :DEL]
[INS: in :INS] expensive [INS: when :INS] compared to [INS: the :INS] whole-genome approach and
[INS: is :INS] still capable [DEL: to :DEL] [INS: of :INS] retain[INS: ing/detecting :INS]
important information.



8) Silvie Belaskova
This paper considers an investigation of the influence of using program Mathematica in mathematical
 education [DEL: on  :DEL] [INS: at  :INS] the level of knowledge and skills of [INS: the  :INS] st
udents [INS: at the  :INS] Faculty of Applied Informatics.  Program enviroments of dynamic mathemat
ics systems are introduced and special attention is devoted to the most expanded product[INS: s :IN
S]  [SB23] from this field, which are Mathematica, AcroTex, Maple. In the main part of this paper,
dealing with [SB24] our pedagogical research, a structure, organization of the experiment, includin
g its statistic evaluation using modern statistical methods in a program Statistica, are described.

9) L. Homola (A. Holcikova, M. Kyr, I. Valaskova)

Cystic Fibrosis Patients Homozygous for F508del Are Not Different at the Beginning

BACKGOUND: The relation between Cystic fibrosis (CF) genotype and phenotype [DEL: w :DEL] [INS: h
:INS] as [DEL: many t :DEL] [INS: been reported on many occasions during past research. :INS] [DEL:
imes reported. :DEL] F508del is considered to be [DEL: the :DEL] [INS: a :INS] mutation with severe
symptoms. We tested whether the patients homozygous for F508del have earlier CF manifestation and
different first symptoms compared to the patients with alternative CF genetic background.

METHODS: [DEL: A d :DEL] [INS: D :INS] ata w[INS: as :INS] [DEL: ere :DEL] obtained from 52
patients from Southern Moravia CF centre from 1977 [DEL: till :DEL] [INS: to :INS] 2008. Patients
were divided into two groups: the group of homozygotes F508del with 26 subjects[INS: , :INS] and
the group of other CF mutations[INS: , :INS] [DEL: :DEL] [INS:  also :INS] with 26 subjects. [INS:
The data :INS] [DEL: C :DEL] [INS: c :INS] ollected [DEL: data :DEL] [INS: included :INS] [DEL:
were :DEL] year of birth, very first symptom typical for CF mentioned in the personal history and
very first appearance of this symptom. The data for both groups w[INS: as :INS] [DEL: ere :DEL]
[INS: then :INS] compared.

RESULTS: No statistical difference has been found between the two groups for the time of
manifestation (p=0.385) and initial symptoms (p=0.888). [INS: The :INS] [DEL: M :DEL] [INS: m :INS]
ost common time of the first CF symptom appearance is from 1 month to 16-20 months of age for both
groups. The group of other mutations has a greater variability. A typical first symptom is a
failure to thrive[SB25] [INS: , :INS] and loose fatty stools (49-50%). [INS: This :INS] [DEL: It
:DEL] is followed by a respiratory tract disease (32-35%). The group of other symptoms is minor
(19-15%).

CONCLUSION[SB26] : Patients homozygous for F508del are not significantly different from patients
with a different CF genetic background at the beginning of the disease.

10) Josef Skopalik

Use of Calcium-regulated Photoprotein Aequorin as Intracellular Ca2+ indicators in Follicular
Lymphoma Cells

Aequorin belongs to the group of Ca2+ indicators called Ca2+ regulated photoproteins. Aquorin is
not [INS: a :INS] toxic compound and can be used to measure[DEL: ment of :DEL] intracellular Ca2+
concentration. Aequorin has several advantages in comparison to widely used Ca2+ fluorescent
indicators (Fura-2, Indo-1, Fluo-3), e.g. high signal to background ratio or minor influence to
intracellular Ca2+ concentration. Its only one disadvant[DEL: e :DEL] [INS: a :INS] ge is the
relative difficult incorporation into cells, because aequorin is 22kDa protein. Ca2+ intracellular
concentration in follicular lymphoma cell were intensively studied in last decade. Suitable methods
of incorporation of aequorin into follicular lymphoma cells and measurement of intracellular Ca2+
by aequorin have not been published yet.

   Method for incorporation of aequorin into the cells based on Hypoosmotic solution treatment was
gradually modified and used to load[DEL: ing of :DEL] aequorin into [INS: the :INS] cytoplasm of
follicular lymphoma cells in our laboratory. The measurement of fluorescence was performed by a
home-made apparatus using photomultiplier (Hammamatsu).

 The improved method of incorporationis is effective for aequorin loading into follicular lymphoma
cells in vitro and ratio of cell survival of the procedure is high.It could be anticipated that
this method can used for intracellular Ca2+ concentration measurement in other types of nonadherent
blood cells. [INS: quit :INS]

11) Pavel Nepustil

You Can Make It Without Treatment: Transforming Identity After Quitting Long-term Methamphetamine
Use

In this article I summarize the partial conclusions of my dissertation „Identity transformation of
former illicit drug users.“. The main goal of my study is to describe a process of quitting
[SB27] long term illicit drug use in the framework of social psychological perspective with the
application of social constructionist theory. I draw from my own research (Nepustil, 2008) in which
I interviewed 20 people who stopped long term methamphetamine use [DEL: more :DEL] [INS: in excess
of :INS] [DEL: than :DEL] 5 years ago. I offer an interpretation of the process which they were
subject to at the level of self and self-identity. From this standpoint[INS: . :INS] I distinguish
between four inter-related components – development of self-agency, development of reflexivity,
creation of commitments and finding [INS: a :INS] new ethical framework - which together create
[INS: a :INS] form of self-identity which is always unfinished. The notion of identity which I
[DEL: was :DEL] [INS: drew upon :INS] [DEL: drawing from :DEL] show[INS: ed :INS] [DEL: s :DEL]
that these processes cannot be maintained without interaction with other people who ideally
contribute to the development of reflexivity and self-agency and they also mediate the new ethical
frameworks. Even if new commitments may be formulated within these relationships, it seems to be
necessary to formulate these commitments in one´s own inner dialogue. All these processes mentioned
[INS: here :INS] are directed to the situation when one is able to connect his past, present and
future goals, to make one´s own decisions based on the choice from range of possibilities and to
orient oneself in a moral space. The possible task of experts on this level is to temporarily
substitute or mediate such support relationships to people who do not have them at hand.

12) Zdenek Novy

Arbitration Clause as Unfair Contract Term from the perspective of [DEL:
:DEL] Czech and EC Law

The conflict between EU consumer protection provided for by the Directive on unfair terms in
consumer contracts and principles of arbitration came to a head in the ECJ's[SB28]  Claro case.
This case has shown that the arbitration clause may be an unfair contract term[INS: , :INS]
par excellence. I use this case as a point of departure for the considerations on unfairness of
arbitration clause in contracts between businesses and consumers. Consequently, I draw a
parallel between the Claro case and the lasting contractual practice in the Czech Republic where
the arbitration clauses incorporated in standard form contracts between businesses and consumers
are in many instances unfair. Their unfairness stems from the fact that arbitration clauses refer
to arbitrators ad hoc who are unilaterally appointed and paid by businesses. Since standard form
contracts are proffered by businesses, consumers are not given an opportunity to negotiate about
the contract. This state of affairs in the Czech Republic is at variance with the Directive on
unfair contract terms as well as the ECJ's case law which provides its interpretation. From the
structural viewpoint, first I [DEL: am going to :DEL] briefly [DEL: inform  :DEL] [INS: refer to
:INS] [DEL: about :DEL] the consumer protection provided by the Directive. Subsequently, I [DEL:
deal :DEL] [INS: examine :INS] [DEL: with :DEL] the ECJ's cases [INS: that :INS] hav[DEL: i :DEL]
[INS: e :INS] [DEL: ng :DEL] an [DEL: importance :DEL] [INS: influence on :INS] [DEL: for :DEL]
further considerations regarding [INS: the :INS] unfair nature of arbitration clauses while putting
particular emphasis on the ECJ's Claro case. Then, I aim to show that the Directive has not been
correctly implemented into Czech Law. As a [DEL: next :DEL] [INS: penultimate :INS] step, I would
like to [DEL: offer :DEL] [INS: propose :INS] a possible solution for this unsatisfactory situation
in the Czech Republic with the help of comparative insight into legal orders of the Member States.
Finally,[DEL:   :DEL] the development of the view on arbitration clauses as unfair contract [DEL:
:DEL] terms in the EU is reflected[INS: upon :INS] .
________________________________

 [SB1]The aim of this thesis is/This thesis aims to

 [SB2]As there are probably several possible solutions, use the indefinite article here until the
chosen one has been named

 [SB3]Methodology…?

 [SB4]unclear

 [SB5]minimize repetition of grammatical structures; this section could start with: The theoretical
section…OR…

 [SB6]see comment SB5

 [SB7]unclear

 [SB8]definite article not needed here

 [SB9]check meaning

 [SB10]misplaced outside of the brackets..?

 [SB11]?

 [SB12]? give full form once before presenting the acronym

 [SB13]Not needed

 [SB14]?

 [SB15]?

 [SB16]Avoid use of phrasal verbs; use examines/

 [SB17]This sentence is too long for the reader to follow with ease

 [SB18]What does this mean?

 [SB19]perceptions?

 [SB20]?

 [SB21]?

 [SB22]Avoid this where possible; use the passive instead

 [SB23]unclear

 [SB24]avoid use of phrasal verbs

 [SB25](do you mean ‘grow’?)

 [SB26]Could be more refined

 [SB27]Colloquial (use renouncing/suspending…)

 [SB28]Use full form first