Vojtech Cultural as pure, natural as impure? Construction of symbolic boundaries among Gypsies in Slovakia There has been an ongoing debate in contemporary anthropology whether and to what extent it is meaningful to separate categories such as nature and culture[JM1] . An insight into Romany/Gypsy settlements in the region of Spiš in central Slovakia brings an interesting empirical material [JM2] – not only [DEL: because of that till :DEL] [INS: due to the fact that until :INS] now the question of the relationship between Gypsies and nature has not been virtually[JM3] discussed. [INS: This :INS] [INS: s :INS] [DEL: S :DEL] tudy draws on [DEL: the :DEL] field research that took place between 2007 and 2011. It lasted for approximately four weeks and was executed in six settlements where traditionally-settled Gypsies live[JM4] . The outcomes of the field research compared to scholarly literature indicate that the concept of defining boundaries with majority and ritual impurity [JM5] may be relevant for the relationship of local gypsies to their natural environment. Moreover, it implies there are numerous similarities in the relationship between Gypsies and the majority and between Gypsies and nature. Text[JM6] considers the traditional nature–culture dichotomy and comes to a conclusion that other dichotomies such as[INS: , for example, :INS] [DEL: e.g. :DEL] wild/domesticated or the chaos/cosmos and physis/nomos divisions of ancient Gree[INS: k :INS] [DEL: ce :DEL] thinking might be more relevant. Text[JM7] also makes [INS: a :INS] clear connection between the system of ritual impurity and defining boundaries against the wild/unknown. Study[JM8] finds culturally specific features in relation to nature in two areas: in [INS: the :INS] markedly non-agricultural nature of [INS: the :INS] Gypsy way of life and in defining boundaries between the pure and the impure (considering nature as an abstract principle). Study[JM9] identifies key areas where this delimitation takes place, to describe the nature of construction of symbolic boundaries and to find out which aspects are specific for Gypsies in Spiš. Finally the research clearly concludes that at least seven dimensions are relevant for consider[INS: ation :INS] [DEL: ing :DEL] : spatial distribution, relationship to the woods, night, animals, women, corporeality, and flowers. Frantisek Abstract Classic Title: Complex Geophysical Survey of the locality Ledové sluje (Ice Caves) in Podyjí National Park Alternative Title: Subsurface Mystery[JM10] of Ice Caves in Podyjí National Park Ledové sluje (Ice Caves) are count[INS: ed :INS] among [INS: the :INS] unique landforms in Podyjí National Park (Czech Republic). There is an extensive system of pseudokarst caves and block fields developed from rock slides on the NW slope of the locality. This area has been known since [INS: the :INS] mid[DEL: dle of :DEL] 19th century, but a mechanism of genesis [JM11] is still not completely explain[INS: ed :INS] . The theories have involved complex of processes such as the Dyje river lateral erosion[JM12] , tectonic effects (faults) and trigger event (earthquake). Those theories were based on geological, geomorphological, spelaeologistical research[DEL: es :DEL] and on test geophysical survey [JM13] (Pospíšil, 1996). The new complex geophysical survey will be describe[INS: d :INS] in [INS: this :INS] [DEL: following :DEL] [INS: paper :INS] [DEL: text :DEL] . The measurements have been made [INS: using :INS] [DEL: with :DEL] [INS: the following :INS] methods: Georadar (GPR pulseEKKO PRO) and 2D Multi-Electrode Resistivity and IP Tomography. The GPR data postprocessing[DEL: have :DEL] contained advanced corrections (included time-depth conversion with 2D velocity model[INS: , :INS] etc.). The subsurface images were integrated in [INS: a :INS] detail[INS: ed :INS] terrain model from laser scanner station and [INS: were :INS] also matched with cave[DEL: s :DEL] maps. The results indicate [INS: a :INS] new fault with high signification to relief development. Second[INS: ly :INS] , the new possible place of pseudokarst caves is determin[DEL: at :DEL] ed. Third[INS: ly :INS] ,[DEL: a :DEL] alluvial deposits [INS: from :INS] [DEL: of :DEL] [INS: the :INS] Dyje river [INS: we :INS] [DEL: a :DEL] re found under the rockslide ([INS: which :INS] could change [INS: the :INS] [DEL: a :DEL] question of age of the Dyje valley). [INS: In addition to this, the paper will :INS] [DEL: And :DEL] [DEL: to :DEL] clarify [INS: how :INS] [INS: the :INS] whole spatial situation is use[INS: s a :INS] [DEL: d :DEL] 3D model with terrain and subsurface layers. Jitka CONCEPTUAL/THEORETICAL PAPER Service Lifecycle according [INS: to :INS] SSME Abstract Service lifecycle belongs to several unexplored and undescribed terms in[INS: the :INS] SSME[JM14] field. In contrast [INS: to :INS] [DEL: of :DEL] given definition[INS: s :INS] of service system[INS: s :INS] , given service characteristic[INS: s :INS] and service system lifecycle[INS: s :INS] , the deep study of service lifecycle is missing. This theoretical paper[DEL: is :DEL] aim[INS: s :INS] [DEL: ed :DEL] to fill in this gap.[INS: :INS] Firstly, [INS: the :INS] background of SSME is briefly presented. The transition from Goods-dominant logic to Service-dominant logic and SSME [JM15] changed not only the economic[DEL: al :DEL] view[INS: , :INS] but [INS: it also :INS] emphasized the service lifecycle instead of product lifecycle. Subsequently, early service lifecycle diagrams ha[INS: ve :INS] [DEL: s :DEL] appeared, each [INS: with its own :INS] distinctive[INS: features :INS] , and from different areas. [INS: The f :INS] [DEL: F :DEL] ollowing [INS: questions concerning :INS] lifecycles [DEL: concerning questions :DEL] are asked in [INS: the :INS] paper[INS: . :INS] [DEL: : :DEL] [INS: Does :INS] [DEL: Covers :DEL] the ITIL service lifecycle [INS: cover :INS] every service area? Is there [INS: a :INS] possibility to describe every service lifecycle by Deming cycle[JM16] ? Is the service lifecycle the same as product lifecycle? Secondly, to answer these questions, the comparison and analysis of th[INS: ese :INS] [DEL: is :DEL] known lifecycles [DEL: i :DEL] [INS: are :INS] [DEL: s :DEL] presented. Analysis has referred to a common characteristic of service lifecycle and has showed Cyclic paradigm as a suitable pattern. Finally the general diagram of service lifecycle is described and is presented for further discussion. Keywords: service science, service lifecycle, SSME Josef Title and abstract of thesis:[DEL: :DEL] Liposome-based vaccine delivery systems[DEL: :DEL] Since the first experiments of vaccination of humans by Edward Jenner against smallpox, the huge effort to achieve [INS: an :INS] effective vaccination strategy has been developed and a lot of knowledge in the fields of vaccination and immunology has been investigated. Vaccination is defined as a process, [INS: through which :INS] [DEL: when :DEL] application of the vaccine stimulates the immune system against the pathogen. [INS: A :INS] [INS: large :INS] [DEL: Gre :DEL] [DEL: at :DEL] amount of vaccination strategies have been developed during past decades[JM17] . First generations of vaccines contained inactivated or attenuated whole cell[INS: s :INS] of pathogen[INS: s :INS] , [INS: whereas more recent vaccines :INS] [DEL: the last one :DEL] are based on sophisticated delivery systems carrying subunit protein[INS: s :INS] . Nowadays, [INS: the :INS] safety of vaccination is emphasised. Thus, subunit protein vaccines lacking potentially dangerous whole pathogen[INS: s :INS] are preferred. Unfortunately, these types of vaccine do not stimulate [INS: the :INS] immune system sufficiently until after adding other components[INS: , which :INS] instruct[DEL: ing :DEL] the immune system to [INS: respond :INS] strong[INS: ly :INS] [DEL: response :DEL] towards the antigen. Moreover, it has been shown recently that activation of specific type[INS: s :INS] of immune response to [DEL: a :DEL] certain pathogen[INS: s :INS] is necessary to be protective against disease. It is a [DEL: big :DEL] [INS: major :INS] challenge to develop new vaccine delivery systems covering issues of effectiveness, safety and also economic cost-benefit[INS: s :INS] . Recently developed antigen delivery systems are based on biodegradable polymer microspheres, such as poly(lactic-co-glycolic acid) or chitosan, micelles and liposomes. Liposomes are very promising for antigen delivery due to their versatility, biocompatibility and capacity to carry several active compounds together[JM18] . This allows [INS: a :INS] synergistic effect [INS: among :INS] [DEL: of :DEL] all components. It was found[DEL: , :DEL] that liposomal surface bound antigen combined with lipophilic derivatives of muramyldipeptide is suitable for induction of strong Th1 type immune response in mice. Importantly, no pyrogenicity in rabbits was measured. In-vitro tests confirmed the activation of dendritic cells, that initiate immune response. The strategy of vaccination is one of the most promising approach[INS: es to :INS] preventing [DEL: people from :DEL] [INS: the spread of :INS] infectious and parasitic diseases[DEL: , :DEL] [DEL: which :DEL] [INS: and it :INS] is hoped [INS: that they may be able :INS] to fight against major killer diseases of the world such as malaria, HIV and cancer. Nicole Macroalgal shifts on Lakshadweep atolls: herbivore size and environmental factors Coral-macroalgal phase shifts have received a great deal of attention[JM19] . Studies, however, often suggest that we do not yet understand the process thoroughly. We studied the herbivory and phase shift relationships on [INS: the :INS] Lakshadweep [INS: I :INS] [DEL: i :DEL] slands, where fish populations are untouched by fishermen. The study explores how these relationships differ among different parts of the reef and how different sized herbivore groups may play different roles in the coral-macroalgal balance, as larger herbivore fish are thought to play [INS: a :INS] major role in keeping reefs in [INS: a :INS] coral-dominant stage. We experimentally manipulated herbivore density on Agatti atoll using exclusion cages of two mesh sizes. One excluded all fish and urchins; the other excluded only large fish. Both cages (40x40x20 cm), with controls, were installed on 24 sites. [INS: The s :INS] [DEL: S :DEL] ites were grouped into pairs: A) closer to the reef crest, B) closer to the lagoon. The sites were situated along the reef starting from the lagoon's main channel[INS: , :INS] moving further onwards along a gradient of [INS: the :INS] water current. After 5 months macroalgae in small-mesh cages settled at 11,3 mm height with 100% coverage, however the big-mesh cages underwent no significant change (height 2 mm, 52% coverage). There was also significant difference in algae growth between sites A and B, and along the gradient, suggesting that the decline of herbivores may have different impacts under different environmental conditions. Our results indicate that the importance of small herbivores may have been very underestimated and suggest that the mechanisms of coral-macroalgal phase shifts may be more complicated and site-specific than earlier thought. Anna[INS: : :INS] [DEL: :DEL] Introduction The atmosphere is the dominant medium for mercury transportation in the environment. When the mercury is released in [INS: the :INS] atmosphere, it becomes a subject of various physical, chemical and photochemical processes and interactions. [INS: The i :INS] [DEL: I :DEL] mportant characterisation[DEL: , :DEL] that distinguishes mercury from other elements in [INS: the :INS] atmosphere, is its ability of re-emission into [INS: the :INS] atmosphere again after [DEL: the :DEL] retention in the soil [1-3]. Atmospheric mercury exists primarily in three forms. [INS: The p :INS] [DEL: P :DEL] redominant form in ambient air is a gaseous elemental mercury Hg^0 (GEM). GEM comprises over 95% of total gaseous mercury [3,4]. In the atmosphere Hg^0 may be oxidised by ozone, alkyl peroxides, radicals, peroxides and halogens to Hg^2+ compounds, commonly including HgCl[2], Hg(OH)[2] and HgBr[2]. Oxidised mercury compounds are called reactive gaseous mercury RGM, [INS: which are :INS] usually defined as the gas phase mercury compounds that can be collected with potassium chloride sorbent [3]. Mercury associated with particulate matter (PM) is called particulate-phase mercury Hg(p). This Hg(p) is not the major form of mercury emitted directly to the atmosphere, but it is often formed through adsorption or partition of gaseous mercury or its compounds on the particle surface [4]. Some fly ashes may capture mercury which would otherwise be emitted into the atmosphere. Great attention has been paid to the capture of mercury by unburned fly ash carbons. Fly ashes capture different species of mercury depending on their nature and the type of anisotropic particles[INS: , :INS] or on the type of unburned carbon [5,6]. Rudimentary particles are important in mercury transformation system[INS: s :INS] and are emitted by combustion of fossil fuels. There is a lot of Hg(p) associated with very fine particles of elemental carbon (mostly <2 μm) due to its adsorbing capabilities [4,7]. [INS: The a :INS] [DEL: A :DEL] mount of adsorbed elemental mercury on particles is not really important, but [INS: 2 to 35% of Hg compounds :INS] [DEL: there :DEL] can be absorbed [DEL: 2 to 35% of Hg compounds :DEL] (mainly HgCl[2], Hg(OH)[2], Hg[2]Cl[2], HgBr[2], HgSO[4], CH[3]HgCl and (CH[3])[2]Hg) [8]. [INS: O :INS] [DEL: Ano :DEL] ther mercury compounds associated with particles are HgS and HgO. Due to their insolubility they occur in solid phase [4,8]. Compounds are deposited through different ways and due to their different physical and chemical properties they play different role[INS: s :INS] in [INS: the :INS] mercury cycle and its impact on [INS: the :INS] environment [4]. Ash particles also act as catalytic sites for oxidation and reduction reactions of mercury (e.g. photolytic reduction of Hg(II) to Hg^0) [8,9]. Most [DEL: of :DEL] atmospheric aerosol mass is comprised of SO[4]^2-, NO[3]^-, NH[4]^+ and H^+, organic matter (quarrels, pollen, viruses, bacteria), earth crust material (weathered soil, dust), water, and marine salt. Fine-particle aerosol contains [INS: a :INS] significant amount of carbon (elemental and organic) and some transitional metals [5]. In this paper, the characterisation of mercury forms in urban PM samples were studied. Dust samples were collected in four localities with high traffic density in Prague[INS: . :INS] [DEL: , :DEL] [INS: S :INS] [DEL: s :DEL] amples were homogenised and the PKC sample was sieved into three particle size samples (see 2.1.). To assess the distribution of mercury species in particles, the extraction method according to Wang [10] was applied. Wang´s method was developed for the understanding of accumulation and transformation of mercury species in soils[INS: , :INS] in relation to the deposition [JM20] of atmospheric mercury. To obtain the Hg portion bound to sulphides, the procedure of sequential extractions was modified according to Fernández-Martínez [11]. It consists[INS: of :INS] [DEL: from :DEL] two stages: the first [DEL: one :DEL] is based on a nitric acid leaching, and [INS: the :INS] [DEL: in a :DEL] second [INS: is based on a :INS] [DEL: stage :DEL] saturated solution of sodium sulphide[INS: , which :INS] is used for HgS extraction to form the soluble Hg polysulphides [11]. Beside[INS: s :INS] sequential extractions[INS: , :INS] a thermal desorption method was utilised for the thermal mercury release. An adsorption of elemental mercury on the particles surface was also studied. Marketa Nationalism and political parties in Romania and Bulgaria: nationalist ideas (not only) for radical right[1] Abstract Th[INS: is :INS] [DEL: e :DEL] paper examines the scope and role of nationalism in the current party politics in Romania and Bulgaria. Some studies [JM21] have dealt with nationalism in Central and Eastern Europe (CEE) mostly only between radical or extreme right parties. Therefore this paper focuses on all relevant political parties (PP) [JM22] to receive complex information about the role of nationalism. It aims to show importance of nationalist rhetoric for political parties in electoral competition (party programmes) of PP[JM23] [JM24] and political discourse (debate) in party systems (PS). [INS: M :INS] [DEL: The m :DEL] ixed qualitative research methods are applied for these two levels. In order to find nationalist position of the party programmes the content/text analysis is used. The political debate is explored by discursive analysis of leader’s proclamations and through the interviews[JM25] . Based on the concept of “political opportunities structure” we assume this paper shows us [JM26] different level of nationalist rhetoric used in current politics in the countries with same initial condition[JM27] . We verify our theoretical assumption [JM28] about the presence of minorities and legacy of communism opened the space for nationalist topics and rhetoric to be strongly presented [INS: in the :INS] [DEL: on :DEL] political scene[JM29] . The analysis shows the high level [INS: o :INS] [DEL: i :DEL] f importance of nationalism between all political parties in party competition and party systems of Romania and Bulgaria. Most likely it is influenced by the previous regime but it would need additional analysis of the reasons for that situation. Belma Docosahexaenoic acid is a promising agent sensitizing colon cancer cells to TRAILinduced apoptosis Belma Skender 1,2, Alena Vaculova 1, Mary Pat Moyer 3, Alois Kozubik 1,2, Jiřina Hofmanova 1,2 1Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Královopolská 135, 612 65 Brno, Czech Republic; 2 Department of Animal Physiology and Immunology, Faculty of Science, Masaryk University, Terezy Novákové 64, 621 00 Brno, Czech Republic 3 INCELL Corporation, LLC, San Antonio, Texas, USA [INS: :INS] Poly[INS: u :INS] nsaturated fatty acids (PUFAs) have been shown to influence the development of colorectal cancer. Docosahexaenoic acid (DHA) is a PUFA of n-3 series, with unique abilities that al[INS: l :INS] ow it to affect diverse physiological processes including cell membrane function and different cell signaling pathways, thus providing protection against various human diseases. It is also documented that DHA can modulate events that are associated with induction of apoptosis in cancer cells. We hypothesized that DHA exerts beneficial effects in sensitizing colon cancer cells to apoptosis induced by TRAIL (tumor necrosis factor-related apoptosis inducing ligand). [INS: :INS] TRAIL is a tumor necrosis factor family cytokine[INS: , :INS] which selectively induces apoptosis in cancer cells while sparing normal cells. Because of these unique selective effects, it is considered as a promising anticancer agent. However, some cancer cells including [INS: those in the :INS] colon are resistant to TRAIL-induced apoptosis. Here we showed that DHA can stimulate TRAILinduced apoptosis in colon cancer cells, which was accompanied by enhanced activation of caspases-8 and -3, and cleavage of caspase substrates. At the same time, caspase-2 and -10 remained unaffected We also demonstrated [INS: the :INS] [DEL: an :DEL] important role of mitochondrial apoptotic pathway in the effects observed, and [INS: provide :INS] [DEL: bring :DEL] evidence of potent stimulation of proapoptotic Bcl- 2 family proteins[INS: , :INS] such as Bax and Bak[INS: , :INS] following combined treatments. A significant downregulation of selected inhibitor of apoptosis proteins (IAPs) was also observed in the cells treated with DHA and TRAIL. While pretreatment with physiologically relevant concentrations of DHA[INS: , :INS] followed by subsequent treatment with TRAIL[INS: , :INS] induced apoptosis in several different colon cancer cell lines, it was not harmful to normal colon epithelial cells. [INS: :INS] This supports the selective cytotoxic effects of the interesting drug combination on colon cancer cells. Our research highlights an important role of DHA in modulation of colon cancer sensitivity to TRAIL-induced apoptosis. This work was supported by grants No. 524/07/1178, P301/11/1730, 301/07/1557 and 303/09/H048 of Czech Science Foundation and AVOZ5004050 AS CR. Jan In the authorship identification problem, [DEL: there are given :DEL] examples[INS: are given :IN S] of short writings of N authors and an anonymous document written by one of these N authors. The task is to determine the authorship of the anonymous text. This problem is predominantly solved wi th machine learning methods. [INS: The properties of an :INS] [INS: i :INS] [DEL: I :DEL] ndividua l document[DEL: ’s properties :DEL] (such as words or n-grams)[INS: , :INS] or a similarity betwe en document and author are mainly used as attributes for the machine learning. [INS: :INS] An experiment was conducted to extend attributes by the ranking of similarity between a document an d an author[INS: , :INS] [DEL: : :DEL] transform[INS: ing :INS] the similarity between the unknow n document and one of the N authors[INS: , :INS] to the order in which the author is the most simi lar to the document in the set of the N authors. The comparison of the similarity probability and t he similarity ranking was made using Support Vector Machines algorithm. Results showed that machine learning methods perform slightly better with attributes based on the ranking of similarity[INS: , :INS] than with previously used similarity of an author and a document. ________________________________ [1] The title and abstract of paper for academic journal. Paper is currently in progress, up to now with preliminary results. ________________________________ [JM1]Would it be useful here to say how long this debate has been going on? [JM2]...identifies and interesting empirical question/debate? [JM3]What does this refer to? [JM4]Were these 6 settlements all in the same region, or how far apart were they? Maybe add a brief statement to contextualise. [JM5]I’m not sure of the concept here [JM6]This text or others? [JM7]Same as last comment, but once you established that it is „this study“, subsequent references would start with „the text/study“ [JM8]Same as last comment [JM9]Same as last comment [JM10]I prefer this title, but would advise using a more technical or critical term than mystery. [JM11]What does this refer to? And does this connect to the mystery of the title? [JM12]Processes of erosion are not theories. You could say the theories have been connected to, or explained by, complex processes... [JM13]Is this a specific single concept? It doesn’t work as an independent grammatical sequence. [JM14]Use the full form the first time you mention it and add the acronym in brackets. On second use you can just use the acronym. [JM15]As an additonal item to the transition, the concept is not clear. If it means the transition „in“ the SSME it would be clearer. [JM16]Is this a specific concept? [JM17]Can you be more specific about the time scale here? [JM18]Several suggests together, so this may not be needed [JM19]Can you add a time frame to this? [JM20]Deposits of? [JM21]Would it be useful to be specific about which studies you are referring to here? [JM22]There is a tendency not to use acronyms for noun compounds less than three words. Aldo if you refer to party programmes frequently as well, the PP could be misleading. [JM23] [JM24]Note three potential PPs in this clause [JM25]Who are the interviews with? [JM26]Avoid we as a single author. „it is assumed that this paper shows different...“ [JM27]Does this refer to the former Eastern Bloc states? [JM28]Theoretical assumptions are verified... [JM29]Media? (in public) Or „in political circles“ (less public)