Petra

Abstract of poster presentation

     Title: Polycyclic aromatic hydrocarbons and endocrine disruption: the role of junctional
                                    intercellular communication


Petra Kubincova^1, Jiri Novak^1, Aneta Dydowiczova^1, and Iva Sovadinova^1

^1Research Centre for toxic Compounds in the Environment, Masaryk University, Kamenice 126/3, 625
00 Brno, Czech Republic, E-mail: kubincova@recetox.muni.cz


The male reproductive function in animals and humans is considered to be highly sensitive system to
many chemicals and physical agents. They are especially generated by industrial or agricultural
activities. Recently many worrying trends are observed in male fertility, such as decreasing sperm
counts, deteriorating semen quality or increasing frequencies of malformations of testis and
incidence of testicular cancer. Endocrine-disrupting chemicals (EDCs) are discussed as a possible
cause of these adverse trends in [DEL: the :DEL] male reproductive health.

There is [DEL: a :DEL] strong evidence, in estrogen- and androgen-mediated processes, that
testicular cell-to-cell communication[INS: , :INS] mediated by gap junctions (termed gap junctional
intracellular communication (GJIC))[INS: , :INS] is involved in important testicular pathways.
Thus, untimely inhibition of GJIC during critical stages may result in male reproductive
dysfunction leading to infertility. Many chemicals known to be EDCs modulate GJIC in gonadal or
non-gonadal cells. However, there is limited information on [INS: the :INS] [DEL: a :DEL]
detail[INS: ed :INS] role of GJIC in adverse reproductive effects caused by specific EDCs.

Recent studies indicate that anthropogenic air pollutants can possibly impair reproduction of
human[INS: s :INS] and wildlife. This study addresses [INS: the :INS] [DEL: an :DEL]
endocrine-disrupting potential of air pollution as a source of compounds [INS: that may :INS]
alter[DEL: ing :DEL] male fertility. The inhibition of GJIC by PAHs and air samples was measured in
testicular cells in this experiment, to determine whether PAHs may cause endocrine disruptive
effects through closing gap[INS: s in :INS] junction channels.

Th[INS: is :INS] [DEL: e :DEL] research was supported by the SoMoPro project no. 2SGA276[INS: :INS]
4 (funded from the European Community within the Seventh Framework Programme (FP/2007-2013)[INS: ,
:INS] under Grant Agreement No. 229603 and co-financed by the South Moravian Region) and by the
Brno PhD Talent Financial Aid from Statutory city of Brno to Petra Kubincova.


[INS:
:INS]

[INS:   :INS]

Helena

3D Models and Their Use for Urban Climate Modelling - Annotation
[INS: :INS]

The thesis[DEL: gives :DEL] [INS: provides a :INS] general overview of methods of creation and use
of 3D urban
models[INS: , :INS] including urban climate applications. Practical analysis of a 3D urban
model of a part of the city of Brno has been carried out[JM1] . The main task of this
thesis was to complete the database of the 3D building model with data needed
to determinate the parameters for the study of spatial differentiation of
thermal urban environments. The parameters under study describe partly built-up
areas[INS: and :INS] [DEL: , :DEL] partly natural conditions of the study area. Comparison of the
acquired
parameters with a land surface temperature map and computation of correlation
indices is included. The thesis proved that orography is a dominating factor
influencing the thermal conditions of Brno, and other characteristics are of
minor importance[JM2] .


[INS:
:INS]

[INS:   :INS]

Lucie


   The UN Security Council Resolution 1267(1999) and Following: Obstinate [JM3] Fight of the UN
                                  against International Terrorism

                                            (Abstract)


   For the last 10 years we [INS: have :INS] [DEL: all are :DEL] witnesse[INS: d a number :INS]
[DEL: s :DEL] of [DEL: many :DEL] attacks [INS: by :INS] [DEL: of :DEL] Al-Qaida terrorists[INS: ,
:INS] as well as [INS: the counter-terrorism :INS] measures[INS: used in :INS] trying to avoid
them. One of the most important actors in this field, acting on the international level, is the
United Nations. This organization has adopted through its body[INS: , :INS] [DEL:  - :DEL] the
Security Council[INS: , :INS] [DEL:  - :DEL] many resolutions [INS: that :INS] deal[DEL: ing :DEL]
with this issue.

   The submitted contribution monitors UNSC resolution 1267 (1999) and [DEL: following :DEL] [INS:
subsequent :INS] resolutions relat[INS: ed :INS] [DEL: ing :DEL] to the matter[INS: . More :INS]
[DEL: , :DEL] concretely[INS: , :INS] it is focused on the process of listing and delisting of
alleged Al-Qaida terrorists. Further the paper highlights the problematic issues of the mentioned
processes with regard to the right to a fair trial of every individual. Finally it shows that even
after the creation of the Office of [INS: the :INS] Ombudsperson[INS: , which :INS] [DEL: that
:DEL] should ensure independence and impartiality, the processes are still not in accordance with
the right to a fair trial.

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 [JM1]For what purpose? This would give a stronger context to the abstract.

 [JM2]Can you provide brief examples of other characteristics?

 [JM3]I’m not sure of the connection between the two parts of the title here