Extra reference for pangenome construvtion: Hickey_et_al_2023

Na zkousce si vylosujete jednu z nasledujicich otazek:

1) Genome organization in 2D and 3D, its relation to sequencing methods and analyses

2) Typical workflows for processing NGS data

3) Variant calling with NGS data

4) HiC library preparation and data analysis

5) Chip-seq library preparationa and data analysis

6) Genome assembly from NGS daa and deBruijn graphs

7) Pangenome creation and variation graphs

8) HMM in general, profile HMM and applications of HMMER

Na kazdou otazku si pripravte 10-15 min vysvetleni dane problematiky, napr. s vyuzitim materialu odkazovanych v osnovach kurzu, Stuart a HiC knizka je take v knihovne.