Bioinformatics seminar

Týden 5 - 20. 3. 2024

Karol Pal, Makova Lab, Eberly College of Science, PennState, USA
Former FI MU student (Bioinformatics) and CEITEC doctoral student and staff scientist (Molecular Medicine) now as a post-doc at PennState in Kateryna Makova lab will come to tell us about his work.

Using the methods employed for generating the gapless assemblies of the human female genome and of the human Y chromosome, the Telomere-To-Telomere (T2T) Primates Consortium is building complete genome assemblies for a number of primate species. As part of this effort, we have recently assembled the T2T sequence of the X and Y chromosomes for five great apes (bonobo, chimpanzee, gorilla, Bornean and Sumatran orangutans) and one lesser ape, the siamang gibbon—all are endangered species. The distinct mating patterns of all studied species could be associated with the architecture of the quickly evolving Y chromosome.
The Complete Sequence of Ape Sex Chromosomes