Týden 5 - 20. 3. 2024
Karol Pal, Makova Lab, Eberly College of Science, PennState, USA
Former FI MU student (Bioinformatics) and CEITEC doctoral student
and staff scientist (Molecular Medicine) now as a post-doc at PennState
in Kateryna Makova lab will come to tell us about his work.
Using the methods employed for generating the gapless assemblies of
the human female genome and of the human Y chromosome, the
Telomere-To-Telomere (T2T) Primates Consortium is building complete
genome assemblies for a number of primate species. As part of this
effort, we have recently assembled the T2T sequence of the X and Y
chromosomes for five great apes (bonobo, chimpanzee, gorilla, Bornean
and Sumatran orangutans) and one lesser ape, the siamang gibbon—all are
endangered species. The distinct mating patterns of all studied species
could be associated with the architecture of the quickly evolving Y
chromosome.
The Complete Sequence of Ape Sex Chromosomes