c Bullet point lists Look at the text in three of Zhan's slides below. What is genetic data? Our DNA consists of 4 bases A, C, T and G; so our genetic data is a string of these 4 letters, e.g. ...AGGGGATTTAAA... ■ But at each genetic location a person can have 1 or 2 types, so can encode the genetic data in terms of 0 and Is, e.g. ...0101001010101... Why do we simulate genetic data? • Lots of methods in literature about how to locate disease genes i To assess a method, apply it to data set and compare predicted location with actual location But need data sets with known location of disease gene ... not many of these Use simulated data sets Why is simulating genetic data challenging? Real genetic data is not a random set of 0 and Is There are complex correlation structures due to thousands of years of evolution Realistic simulated data should contain these structures Grammatically inconsistent lists are confusing and difficult to follow. Simplify the text by (1) applying the 'less is more' principle and cutting the number of words and (2) making the bullet points grammatically consistent. Examples Bullet points starting with verbs • Attack market • Simplify product line • Cut prices Bullet points starting with nouns • Market attack • Simplification of product line • Price reduction Bullet points starting with adjectives • Larger market • Simplified products • Reduced prices VB035 - Week 8 Exercise 1) Circle the correct phrase. 1 Who asked you / did you ask to the party?' 'Maria, but she told me she couldn't come.' 2 'Who saw you / did you see at the supermarket?' 'Just Ben, but I don't think he saw me.' 3 'What gave you / did you give the impression that Greg was depressed?' 'Oh, I don't know. He just seemed a bit down.' 4 'Who thought you / did you think had stolen the money?' 'Jenny, but she believed me when I told her I hadn't done it.' 5 'Which programme taught you / did you teach the most?' 'Well, I learned a lot from Extreme History.' 6 'Who borrowed you / did you borrow this book from?' Tracy, and I need to give it back to her tomorrow.' 7 'What brought you / did you bring to this part of the world?' 'Work, really, and I've always loved this country.' 8 'Who accused George / did George accuse of starting the fight?' 'He says that John started it by calling him names.' 9 'Which person admires you / do you admire the most?' 'I think I would say my grandmother because she's worked hard all her life.' 10 'Who told Dave / did Dave tell your secret?' 'I'm not sure, but I think Simone probably told him.' Exercise 2) Complete the question tags. 1 Get me some chewing gum when you go to the shop,.........................you? 2 Let's watch that new DVD you bought today,.........................we? 3 There's not really much point waiting.......______________there? 4 Tonia will put us up for the weekend,.........................she? 5 Nobody seems to like Jessica..........................they? 6 I'm not making much sense now,.........................I? 7 Let's go because it's getting late,.........................it? 8 If you borrow my coat, don't get it dirty,.....................you? 9 Bill should be here by now,.........................he? 10 I'm making you feel uncomfortable,.......................I? 11 Someone left the door open..........................they? 12 Nobody knows about this..........................they?