Biochemistry I                                                                                
   VSBC021s, ZLBC021s

   

   SEMINARY CLASSES  
                                                                                          2nd
   Semester 2008

   

   Week Date                                                                                      
   1    19 – 21  Feb. Introduction into the metabolism of cells (differences between prokatyotic  
                      and eukaryotic cell, compartmentation of metabolic processes, enzyme        
                      markers of cell fractions, non-covalent interactions in the cell and their  
                      significance).                                                              
   2    26 Feb. - 28  Structure of haemoglobin and its relationship to the function. Hb types in  
        Feb.          the blood    of healthy subjects, HbCO and MetHb, abnormal Hb types.        
                                                                                                  
                                                                                                  
   3    4 - 6 Mar.    Enzymes - reaction rate, progress curve, the Michaelis plot and K[m],       
                      enzyme inhibition.                                                          
                                                                                                  
   4    11 - 13 Mar.  Coenzymes, their relationship to vitamins.                                  
                                                                                                  
                                                                                                  
                                                                                                  
                                                                                                  
   5    18 - 20 Mar.  Written test I (Haemoglobin, enzymology, coenzymes.)                        
                                                                                                  
                      Membrane structure and assembly. Transport across membranes.                
                                                                                                  
                                                                                                  
   6    25 - 27 Mar.  Metabolism of glucose: Glycolysis under anaerobic and aerobic conditions    
                      and the oxidation of pyruvate. Gluconeogenesis. Glycogenesis and            
                      glycogenolysis.                                                             
                                                                                                  
                                                                                                  
   7     1 - 3 Apr.   Metabolism of proteins. Common features of amino acid conversion.           
                                                                                                  
                      The synthesis of urea. Nitrogen balance.                                    
                                                                                                  
                                                                                                  
   8    8 - 10 Apr.   Important reactions in amino acid catabolism.                               
                                                                                                  
                                                                                                  
   9    15 - 17 Apr.  Written test II (Membranes, transport across membranes, metabolism of       
                      saccharides and amino acids.)                                               
                                                                                                  
                      Biosynthesis and desaturation of fatty acids. The sources of essential      
                      fatty acids. Metabolism of triacylglycerols.                                
                                                                                                  
                                                                                                  
   10   22 - 24 Apr.  Metabolism of phospholipids. Biosynthesis of eicosanoids. Peroxidation of   
                      lipids.                                                                     
                                                                                                  
   11    29 - 1 May   Written test III (Metabolism of lipids.)                                    
                                                                                                  
                      The citric acid cycle.                                                      
                                                                                                  
                                                                                                  
   12   6 -  8  May   The respiratory chain and oxidative phosphorylation.                        
                                                                                                  
                                                                                                  
   13   13 - 15 May   Written test for the students who did not reach the required result in      
                      preceding tests.                                                            
                                                                                                  
   14   20 – 22 May   Compensatory lessons, consultation. Credits.                                
                                                                                                  
                                                                                                  
   15   --            (Anatomical dissection course.)                                             

   

                               Neglected lessons have to be made up.

                                       by the 15^th of June.

   

   Students are expected to come to the seminary room at least 5 minutes before the start of the
   lesson.

   Attendance in seminars is obligatory. All absences must be justified through the Department of
   study affairs. Illness is usually the only acceptable excuse for absence from class and must
   be officially confirmed. After being absent the student must make up for the study materials
   from the given seminar according to the teachers instructions.  If the student has been absent
   from three or more seminars without serious reasons, the course –unit credit will be not
   given.

   

   Conditions for giving the course-unit credit

   Three short tests are written during the semester. Students that will obtain 70% points or
   more during the semester are not obliged to write the credit test.

   The other students will write the credit test with the 30 questions in the last week of the
   semester. The limit for passing the credit test is 12 points. Students that will not fulfill
   this limit will be allowed to repeat the test once. Remedial dates for writing the credit test
   will be scheduled till 30.6.2008. Students that will not fulfill this requirement will not be
   given the course-unit credit.

   

   Obtaining of course-unit credits of practices and seminars is the pre-requisite for
   registration to the examination of Biochemistry I.