The integration of intermediary metabolism of nutrients
                                   at the tissue and organ level









Basal metabolic rate depends on

    - gender (women about 10 % lower than men),

    - body temperature (increase by 12 % at 1 °C body temperature increment),

    - environmental temperature (increased in cold climates),

    - thyroid status (increased in hyperthyroidism),

    - pregnancy and lactation (increased),

    - long-term low-energy intake (low-calory diets, anorexia nervosa,

    - age (increased in childhood).













After a typical high-saccharide meal, glucose leaves the intestine in high concentrations.

Hyperglycaemia stimulates the pancreas to release insulin,                                 glucagon
release is inhibited.









is the time period from the first feeling of hunger (few hours after a meal), which doesn't last
usually more than 10 -12 h  (e.g. during the nightly starved-fed cycle, till the refed state is
reached again after breakfast)