MOTILITY OF GASTROINTESTINAL
TRACT
Marie Nováková
Jaroslav Winkler
Project FRVŠ/0839/2012
Innovation of teaching of physiology at Faculty of Medicine, Masaryk University –
audiovisual teaching material „Motility of gastrointestinal tract“
PROCESSES PRESENT IN
GASTROINTESTINAL TRACT
• DIGESTION
• ABSORPTION
• STORING
• EXCRETION
serosis (adventicia)
epithelium
muscularis mucosae
longitudinal
layer
circular layer
plexus
submucosus
plexus
myentericus
ENS
muscularisexterna
submucosa
Modified according to: J. Švíglerová: Fyziologie gastrointestinálního traktu, LF UK Plzeň, 2012
GIT INNERVATION
ENTERIC NERVOUS SYSTEM
SYMPATICUS PARASYMPATICUS
Local (short) reflex
Central (long) reflex
CNS
+-
mechanoreceptors
chemoreceptors
CONTINUOUS TONUS OF ANS
FORWARD SIGNALS: SPEED UP, OPEN THE WAY
BACKWARD SIGNALS : SLOW DOWN, CLOSE THE WAY
GIT MOTILITY
CONTRACTIONS tonic
rhythmic
MOVEMENTS propulsive (peristalsis)
mixing
Magnus solution
KCl
NaCl
CaCl2
NaHCO3
38°C
oxygen
ISOLATED INTESTINAL LOOP - RAT
MECH
mechanical stimulus
ISOLATED INTESTINAL LOOP - RAT
STOMACH - RABBIT
SMALL INTESTINE - RABBIT