Photoplethysmographic blood presure measurement/ Department of Physiology 1 Photoplethysmographic blood presure measurement Peňáz´s method, volume-clamp method Photoplethysmographic blood presure measurement/ Department of Physiology 2 Principle of continual blood pressure measurement Arterial lumen (finger volume) Pressure in the cuff Control systemConstant finger volume pressure Before application of control system Control system: Correction of the pressure in the finger cuff according to the arterial lumen changes. Aim: maintaining of constant arterial lumen through pressure changes in the cuff. application of control system cuff Photoplethysmographic blood presure measurement/ Department of Physiology 3 SBP DBP 150/90 127/92 Photoplethysmographic blood presure measurement/ Department of Physiology 4 Extrasystoles supraventricular ventricular Photoplethysmographic blood presure measurement/ Department of Physiology 5 Orthostatic hypotension 6 Valsalva manoeuvre 7 Baroreflex sensitivity, BRS RR interval BRS: slope RR SBP R ECG HR BRSf: slope SBP SBP Blood pressure DBP BRS: change of cardiac cycle caused by SBP change by 1 mmHg [ms/mmHg] Evaluation of cardiac baroreflex function through SBP and heart rate (cardiac cycle) changes 8 Evaluation of BRS Standard(oxford) method: - Application of phenylephrine (vasoconstrictor) decreased BRS • Physiologically • stress • exercise • Pathologically • hypertension • diabetes • Heart failure • Myocardial infarction normal BRSRR STK RR STK decreased BRS