Anatomie a fyziologie NS jednotka: neuron a neurotransmittery Synapse/neurotransmitery Organizace NS Etiologie poruch NS - a -motoneurony) - MOTONEURON) - podle lokalizace Capsula interna sclerosis multiplex Demyelinizace sclerosis multiplex PORUCHY Spoje a neurotransmitery BG Parkinsonova choroba Etiopatogeneze PD - methyl-4-phenyl-1,2,3,6- tetrahydropyridine) Huntingtonova nemoc (chorea) HD - huntingtin Alzheimerova choroba = beta-amyloidopatie a Tauopatie Alzheimerova choroba - demence Alzheimerova choroba - demence Myodystrofie Myodystrofie