AUTONOMIC NERVOUS SYSTEM Functions: Contraction and relaxation of smooth muscles Function of all exocrine glands Heart rate Some metabolic processes https://classconnection.s3.amazonaws.com/360/flashcards/855360/png/untitled1326767508368.png AUTONOMIC NERVOUS SYSTEM qsympathetic NS §ncl. intermediolateralis in T1 – L2 segments of spinal cord = thoracolumbar system §paravertebral ganglia (tr. sympathicus) and prevertebral ganglia §neurotransmitters Øpregangl. – acetylcholine Øpostgangl. – norepinephrin (ex. sweat glands and piloerector muscle) qparasympathetic NS § parasympathetic nuclei of CN III, VII, IX, X § segments S2 – S4 = craniosacral system § ganglia near the target organ § neurotransmitter acetylcholine •Sympathetic system •Catabolic reaction (activities that are mobilized during emergency and stress situations, “fight, fright and flight” responses) Parasympathetic system Anabolic reactions (activities associated with conservation and restoration of body resources, “rest and digest” responses) The sympathetic system stimulates those activities that are mobilized by the organism during stress situations. Increased activity of the sympathetic and following release of adrenergic neurotransmitters prepares the organism for FFF. http://images.slideplayer.com/1/273836/slides/slide_26.jpg Central autonomic network (CAN) Paraventricular nucleus Textové pole: PVN in CAN PVN in CAN DN of CN X rVLM sIMLN cSN of CN V NTS Other hypothalamic nuclei in CAN: Dorsomedial nucleus Posterior hypothalamic nucleus Mammillary nucleus Lateral hypothalamic area - cardiovascular control, control of feeding, satiety and insulin release Extrahypothalamic structures in CAN: Control of symp. outflow Locus coeruleus Rostral and caudal VLM Raphe nuclei Control of parasymp. outflow Central ncl. of amygdala Dorsal ncl. of CN X Raphe nuclei PAG Parabrachial ncl. Limbic cortex – control of both autonomic outflows Cingulate c. Orbitofrontal c. Insula Rhinal c. Hippocampus Modulation of ANS q from brain cortex §tr. corticoreticularis → tr. reticulospinalis → preganglionic neurons qfrom hypothalamus §tr. hypothalamotegmentalis §tr. mammillotegmentalis qfrom hypothalamus and limbic forebrain §FLD → dorsolateral tegmentum qfrom amygdalar complex §→ hypothalamus §→ PAG – coordination of somatic and autonomic response to behavior and defensive reaction → preganglionic neurons of S and PS divisions Descendent modulatory pathways q fasciculus longitudinalis dorsalis (FLD) q q fasciculus telencephalicus medialis (medial forebrain bundle MFB) q tr. mammillotegmentalis Fasciculus longitudinalis dorsalis Fasciculus telencephalicus medialis Tractus mammillotegmentalis Hypothalamus Nuclei of the anterior part q ncl. paraventricularis q stimulation of parasympathetic system q Stimulation of the anterior part of hypothalamus q miosis q decrease in heart rate and blood pressure q dilation of cutaneous arteries q increase in peristalsis and secretion in the GIT Hypothalamus Nuclei of the posterior part q ncl. mammillaris and hypothalamicus post. q stimulation of sympathetic system q Stimulation of the posterior part of hypothalamus q mydriasis q increase in heart rate and blood pressure q constriction of cutaneous arteries q decrease in peristalsis and secretion in the GIT q erection of hairs PUPILARY LIGHT REFLEX q a reflex that controls the diameter of the pupil, in response to the intensity of light (luminance) that falls on the retina of the eye q mydriasis: dilation of the pupil q q miosis: constriction of the pupil http://cal.vet.upenn.edu/projects/giphys/review/plr.gif ACCOMMODATION http://163.178.103.176/fisiologia/neurofisiologia/objetivo_3/Clayman91c.jpg https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcQlokIG-DzLqrSjAFdxazS4tcpxWs3_GRQV5YzFPXfVS9L 7V9ti http://img.youtube.com/vi/RiLX-rbxBKA/0.jpg Near reflex triad: convergence accommodation of the lens pupillary constriction http://image.slidesharecdn.com/refractorymediaofeyes4march10-100313063054-phpapp01/95/refractory-me dia-of-eye-s4-march-10-23-728.jpg?cb=1268461914 Illustrations were copied from: Neuroscience Online, the Open-Access Neuroscience Electronic Textbook Department of Neurobiology and Anatomy University of Texas Medical School at Houston