VENAE The wall of the veins • reduced muscle layer VENA CAVA SUPERIOR •vena brachiocephalica dextra + vena brachiocephalica sinistra (art. sternocostalis I. dextra) •behind art. sternocostalis III. opens out into the right atrium •Vena brachiocephalica: vena jugularis interna + vena subclavia (behind art. sternoclavicularis - angulus venosus) •ductus thoracicus, ductus lymphaticus dexter 1) The collateral branches •From the thyroid gland, the larynx, the trachea •vena vertebralis •vena thoracica interna •From the mediastinal organs 2) The truncal tributaries •vena jugularis interna •vena subclavia Vena brachiocephalica VENA JUGULARIS INTERNA •The cranial cavity, the facial ares of the head, the neck •It starts as bulbus superior venae jugularis internae, behind the sternoclavicular joint it is extended as bulbus inferior venae jugularis internae • •intracranial and extracranial tributaries: •1) The intracranial tributaries •• sinus durae matris (without the smooth muscle and valves) 2) The extracranial tributaries •v. facialis •v. lingualis •from the thyroid gland, the pharynx, larynx and the trachea •v. retromandibularis is created by the confluence of v. temporalis superficialis and v. maxillaris •v. jugularis externa – the subcutaneous vein The ways od the spread of infection from the facial ares into the cranial cavity: v. facialis – v. profunda faciei - plexus pterygoideus v. facialis – v. ophtalmica – sinus cavernosus VENA SUBCLAVIA •It is the continuation of vena axillaris, the border line is the first rib • •The tributaries (small): •• vena transversa colli •vena suprascapularis • VENA AXILLARIS •It starts at the level of the attachment of musculus pectoralis major (at the level of collum chirurgicum humeri), it is created by the confluence of venae brachiales The tributaries: •venae brachiales (the truncal tributaries) • venae thoracoepigastricae: from the subcutaneous areas of the lateral and anterior thoracic wall, they are attached to the subcutaneous veins of the abdomen (venae subcutaneae abdominis) • vena cephalica: the superficial subcutaneous vein of the upper extremity, it runs on the lateral side of the forearm and arm (within sulcus bicipitalis lateralis) and within trigonum deltoideopectorale . •venae costoaxillares – join to the intercostal veins • •vena thoracica lateralis – m. serratus anterior VENAE MEMBRI SUPERIORIS •Two venous systems: •1) The deep veins: •They are usually double and accompany the homonymic arteries •2) The superficial subcutaneous veins: •They create the subcutaneous nets (rete venosum dorsale et palmare manus) On the dorsal side of the hand: • vena basilica – originates from the dorsal venous net as vena salvatella, continues on the ulnar side and opens out into vena brachialis (sulcus bicipitalis medialis) • vena cephalica – is formed on the radial side of rete venosum dorsale manus as vena cephalica pollicis, it continues on the lateral side and opens out into vena axillaris (sulcus bicipitalis lateralis) •These two veins are interconnected through vena mediana cubiti, in the region of the cubital fossa Facies dorsalis Facies ventralis VENA CAVA INFERIOR •It begins on the right side of the lumbar vertebral column at the level of L4 as a connection of vena iliaca communis dextra et sinistra, it opens out into the right cardiac atrium • It has the parietal and visceral tributaries: • •a) The parietal tributaries •• venae iliacae communes •• from the abdominal wall •• from the diaphragm • •b) The visceral tributaries •• from the testicles (ovaries) •• from the renal and suprarenal • glands •• venae hepaticae •• vena umbilicalis •Venae iliacae communes •vena iliaca communis sinistra et dextra begin in front of the right and left art. sacroiliaca as the connection of v. iliaca interna and v. iliaca externa. •Vena iliaca interna •It originates from the venous plexuses of the small pelvis above foramen ischiadicum majus •a) The parietal tributaries •• the branches from the pelvic wall •b) The visceral tributaries •• the venous plexuses around the pelvic organs (plexus uterinus, vaginalis, prostaticus, rectalis) •Vena iliaca externa •It is a continuation of v. femoralis •It begins below the medial part of ligamentum inguinale within lacuna vasorum VENAE MEMBRI INFERIORIS •The deep and superficial venous system •The both systems are interconnected through numerous connections (vv. perforantes) • •a) The deep veins of the lower extremity •They are usually double and accompany the homonymic arteries •The largest of the deep veins is vena femoralis, which continues into the pelvis as vena iliaca externa • •b) The superficial (subcutaneous) veins of the lower extremity •rete venosum plantare et dorsale pedis • from the dorsal venous net starts vena saphena parva et vena saphena magna •• v. saphena parva runs behind the lateral ankle and is the tributary of v. poplitea •• v. saphena magna begins on the medial side of the foot and opens out into v. femoralis vv.perforantes The varices VENA PORTAE •It forms the functional circulation of the liver, it drains the blood away from the unpaired abdominal organs into the liver •It is formed by confluence of vena mesenterica superior and vena lienalis behind caput pancreatis at the level of L2 •Přítoky: • a) Kmenové přítoky •• vena mesenterica superior •• vena lienalis, na rozdíl od tepen bývá většinou přítokem i vena mesenterica inferior •b) Další přítoky •• ze žaludku a jícnu •• venae paraumbilicales The portocaval anastomoses •Connections between vena portae and v. cava superior et inferior, under the patological conditions when the pressure within the stream bed of the portal vein is increased, they widen and enable the outflow of the blood into the caval veins •Connections within the inferior part of the esophagus and the gastric wall •Connections around the umbilicus, which are during extension stellate shaped and are called ,,caput Medusae“ •Connections around the rectum •Burow´s around the urinary bladder •Retzius veins between intra and retroperitoneally veins The cavocaval anastomoses • •The superior and inferior caval vein are interconnected through the use of the special venous systém which are distributed on the sides of the vertebral column, these veins collect the blood from the retroperitoneal area, the posterior abdominal wall, the intercostal spaces, the vertebral column and the posterior mediastinum •The incompletely valves, blood flow in the both directions 1) Plexus venosi vertebrales •2) Vena azygos •It begins below the diaphragm and caudally connects to vena iliaca communis dextra, it opens out from behind into vena cava superior •The tributaries: •• from caudal 8 till 10 intercostal spaces •• vena hemiazygos passes on the right side of the vertebral column, cranially it reaches up to the level of Th7–9 •• they drain the blood away from the organs of the mediastinum and the diaphragm The fetal circulation The blood of the mother and the foetus doesn´t mix! The lymphatic system • • The lymphatic system • it begins in the peripheral parts of the body, leads only centripetally and the termminal sections open out into the veins •it provides the return transport of the water and the metabolites from the interstitial fluid into the blood •System- superficial - deep •Function- dreinage and transport - imunology The lymph •It results from the interstitial fluid •Colourless or milky coloured liquid •Daily: 1,5 till 2 liters of the lymph •The stopping of the drain of the •lymph → lymph edema The lymphatic vessels •They begin blindly •The wall is thin •Numerous valves •Within their course, there are the lymphonodes inserted •lymphatic capillars→ lymphatic capillary plexuses → lymphatic vessels→lymphatic plexuses→lymph ducts The tissues without the lymphatic vessels: hair, nails, epidermis, the sclera, the cornea, the lens, the cartilages, the nervous tissue, the bones The lymph nodes (nodi lymphatici) •capsule + trabeculae •hilus •Cortex – more lymphocytes •medulla – less lymphocytes •convex part - „aferent“ – vasa afferentia (more) •concave hilus - „eferent“ – vas efferens •They filtrate the lymph • •ductus thoracicus §pars abdominalis §pars thoracica §pars cervicalis •ductus lymphaticus dx. 2 main lymph ducts (irregular division of the body) ductus thoracicus (3/4 of the body) • cisterna chyli (below the diaphragm (L1-L2), tr. intestinalis, tr. lumbalis dexter et sinister) • pars abdominalis (retroperitoneally) • pars thoracica (mediastinum posterius, aorta and the esophagus) • pars cervicalis (angulus venosus sinister C7) takes tr. jugularis sin. and tr. subclavius sin., tr. bronchomediastinalis sin. ductus lymphaticus dx. (1/4 of the body) • tr. jugularis dex. and tr. sublavius dex. tr. bronchomediastinalis dx. The lymphatic drainage of the head •n.l. parotidei •n.l. retroauriculares •n.l. occipitales •n.l. submandibulares •n.l. submentales • N.l. cervicales profundi The lymphatic drainage of the tongue •3 directions •+ over the midline of the tongue •The lymphatic drainage of the neck •1. N.l. cervicales superficiales •alongv. jugularis externa •vassa efferentia into n.l. cervicales profundi •2. N.l. cervicales profundi—> truncus jugularis •15-30, Wood´s lymphonode, • along v. jugularis int., n. accesorius, nodi supraclaviculares The lymphatic drainage of the thorax 1.The thoracic walls •Superficial layer → nodi axillares •Innner side of wall → nodi parasternales et intercostales 2. The thoracic organs: •Organs of the mediastinum→ nodi tracheobronchiales sup. et. inf. → truncus bronchomediastinalis •The lymphatic drainage of the lungs •Everything into truncus lymphaticus dexter •Only two superior segments of the right lung – into the thoracic duct !!! • nodi lymphatici: •pectorales (Sorgius) •subscapulares •interpectorales •laterales (humerales) •centrales •apicales (infraclaviculares) Axilla 40 lypmh nodes 6 groups Truncus subclavius plexus lymphaticus axillaris ductus thoracicus ductus lymphaticus dexter plexus areolaris plexus subareolaris plexus circumareolaris The lymphatic drainage of Mamma •nodi lymphatici axillares •nodi lymphatici parasternales •nodi supraclaviculares •intercostální cesta (n. intercostales) The lymphatic drainage of the abdomen 1. The superficial system– nodi axillares - nodi inguinales •The border line is at the level of the umbilicus • 2. The deep system •parietal – along the large vessels •visceral – unpaired and paired abdominal organs (around the unpaired branches of the aorta) The lymph nodes along the large vessels (retroperitoneally): Nodi lumbales—>tr. lumbalis Nodi iliaci communnes Nodi iliaci externi Nodi iliaci interni Nodi parauterini (Bayer)/ nodi retroprostatici Nodi gastrici Nodi pylorici Nodi pancreaticolienales Nodi pancreaticoduodenales Nodi hepatici Nodi mesenterici Nodi colici et paracolici Nodi rectales et pararectales Nodi coeliaci (in front of the aorta) Truncus intestinalis Nodi lumbales Nodi iliaci externi Nodi inguinales profundi The lymph from the pelvic organs– nodi iliaci interni – nodi iliaci communes – nodi lumbales – truncus lumbalis – ductus thoracicus The lymph from the lower limb– nodi inguinales profundi – nodi iliaci externi Nodi iliaci communes Nodi iliaci interni Nodi iliaci communes Nodi lumbales The lymphatic drainage of the upper extremity •The superficial system •The medial collectors •The lateral collectors •The anterior collectors •The deep system •podél velkých cév nodi axillares pl. lymphaticus axillaris nodi brachiales n. l. cubitales profundi truncus subclavius The medial collectors– 10-15, along v. basilica, into axilla – nn. l. axillares centrales et laterales The lateral collectors– 6-7, along v. cephalica into axilla The frontal collectors– from the palm, 4-5, within the cubital fossa they connect to the previous two systems The lymphatic drainage of the lower limb •The superficial system •The lateral collectors •The medial colectors •The posterior collectors •The deep system •Along the large vessels nodi lymf. inguinales profundi (lymphonodus Cloqueti) nodi iliaci externi nodi iliaci communes nodi lumbales N. inguinales superficiales The lateral collectors- from dorsum pedis toward the knee, connect to the medial ones The medial collectors- from planta pedis, along v. saphena magna onto thigh, they enter nodi lymph. ing. sup. The posterior collectors- from heel, along v. saphena parva, inside fossa poplitea they enter nodi lymp. poplitei and then added to the deep lymphatic vessels The lymphography of the pelvis Lymph edema THE THYMUS •The lymphatic • organ •30-40 g •corpus adiposum thymi •T-lymfocyty- • diferentiantion • and maturation • Tonsils (Tonsillae) • agreggation of the lymphatic tissue below the epithelium • production of lymphocytes •Obrázky: •Atlas der Anatomie des Menschen/Sobotta. Putz,R., und Pabst,R. 20. Auflage. München:Urban & Schwarzenberg, 1993 •Netter: Interactive Atlas of Human Anatomy. •Naňka, Elišková: Přehled anatomie. Galén, Praha 2009. •Čihák: Anatomie I, II, III. •Drake et al: Gray´s Anatomy for Students. 2010