Learning unit: Therapeutic index, therapeutic range, therapeutic risk


Importance of the learning unit:

Learning unit introduces general pharmacological aspects of drug safety and its assessment in
considering the risk of pharmacotherapy.


Relevant terms

dose-effect relations

effective and toxic dose

lethal dose

therapeutic range

therapeutic index


Learning outcomes

Student explains the terms therapeutic index, therapeutic range, and therapeutic risk.

Student evaluates safety of an example drug using therapeutic index and therapeutic range
parameters.


Information sources

Rang & Dale's Pharmacology, 8th edition, 2016, chapter 7, pp. 99-100

Study materials for courses aVLFA0721p and aVLFA0721c.


Exam questions

General pharmacology: 23. Pharmacovigilance, drug safety, advertisement and marketing on the field
of therapeutics, ethical issues