Physiotherapy Part A 1. Structure and function of cell membranes and cell organelles 2. Active and passive transport across membranes. Co-transport 3. Compartmentalization of body fluids; differences between intra- and extracellular fluids 4. Ion channels; Intercellular communication 5. Functions of the nerve cell 6. Functional morphology of synapses 7. Generation of resting membrane potential 8. Action potential 9. Molecular mechanism of muscle contraction 10. Electrical and mechanical behaviour of muscle (skeletal, smooth and heart muscle) 11. Neuromuscular junction 12. Blood composition 13. Red blood cell. Haemolysis. 14. Haemoglobin and its derivatives 15. Suspension stability of RBC (sedimentation rate) 16. Immune system 17. Blood groups antigens (ABO group, Rh group) 18. Function of platelets 19. Hemocoagulation, anticlotting mechanism 20. Second messengers Part B 1. Hypoxia 2. Lung ventilation, volumes, measurement. Dead space. 3. Intrapulmonary and pleural pressure. Pneumothorax. 4. Composition of atmospheric and alveolar air. 5. Transport of O[2]. Oxygen – haemoglobin dissociation curve. Transport of CO[2] 6. Regulation of ventilation 7. Functional morphology of nephron 8. Clearance; Glomerular filtration 9. Function of renal tubules 10. Transport of glucose in kidney 11. Counter-current system. 12. Acid-base balance 13. Formation, composition and functions of saliva 14. Gastric production of HCl, its regulation 15. Functions of the stomach 16. Motility of gastrointestinal tract 17. Composition, function and regulation of pancreatic juice secretion 18. Liver functions 19. Digestion and resorption in the small intestine 20. Functions of colon 21. Conduction system of the heart 22. Non-invasive assessment of blood pressure 23. ECG, Estimation of electric axis of the heart 24. Heart as a pump - cardiac cycle - pressure-volume loop; stroke volume and cardiac output 25. Local regulation of blood flow. Special regions of circulation (skeletal, lung, coronary, skin,cerebral) 26. Regulation of cardiac output – Starling principle 27. Periphery resistance 28. Blood pressure. Hypertension. 29. Blood pressure regulation (e.g.orthostatic reaction) 30. Micro-circulation. Lymphatic system Part C 1. Caloric content of food. Direct calorimetry. Indirect calorimetry. 2. Vitamins – overview 3. Energy balance. Basal metabolism 4. Cardiopulmonary response to exercise 5. Physiological significance of positive and negative feed-back 6. Physiological regulations (overview) 7. Homeostasis 8. Metabolism of iron 9. Thermoregulation 10. Sympathetic nervous system (overview) 11. Parasympathetic nervous system (overview) 12. Placental and faetal circulation. Circulatory adjustments at birth 13. Autocrine, paracrine, endocrine regulation 14. General principles of endocrine regulation 15. Hypothalamo-pituitary system 16. Hormones of anterior pituitary gland 17. Formation and secretion of posterior pituitary hormones 18. Effects of thyroid hormones 19. Endocrine pancreas 20. Hyper- and hypoglycaemia. Diabetes mellitus. 21. Regulation of glycemia 22. Adrenal cortex. Functions, malfunctions. 23. Adrenal medulla. Synthesis of catecholamines. 24. Parathormone, vitamin D and calcitonin 25. Antidiuretic hormone. Natriuretic peptides 26. Physiology of reproductive system. 27. Physiology of pregnancy 28. Proprioceptive reflex – reflex arch, examples 29. Exteroceptive reflex – reflex arch, examples 30. Physiology of the sensor systems (eg.vision, hearing) .