CIRCULATORY FAILURE • The main function of circulation is perfusion of organs BP = CO x TPR CIRCULATORY FAILURE BP = CO x TPR CO decrease: ülower volume in circulation – lower venous return üvasodilatation of venous system ülower pumping function of the heart CIRCULATORY FAILURE BP = CO x TPR TPR decrease: ütoxic vasodilatation üDysbalance of autonomy nervous system – sympathetic part – decrease of sympathetic tone of vessels NewYork Heart Association (NYHA) classification