Burns, forst bite, corrosion 1st Department of Surgery University hospital of St. Anne Brno Thermal injuries ●Effect of heat ●Electricity, Radiation, Chemistry ● ● ●Time of exposure ●Type of energy Mechanism of effect ●Dehydratation ●Formation of free radicals ●Denaturation of proteins (60 C´) ●Destruction of DNA mollecule ●Cellular membrane destruction ●Cellular death - apoptosis Epidemiology and etiology ●1% of population per year ●97% ambulatory, 3% hospitalization ● ●40% children ●Hot fluids 60% ●Open flame 25% ●Electricity 3,5% ●Chemical burns 4% ●Radiation 1% Types of burns ●Thermal injuries ● ●Electricity burns ● ●Chemical burns -corrosions ● ●Radiation burns Types of burns –by depth of injury ●Grade I ●Grade II – Grade IIA ● - Grade IIB ●Grade III ●Grade 4 Grade I - combustio erythematosa ●Injury to the epidermis, dermis intact ●Erythrema ●Pain (48hours) ●No scarrification ●Time of healing 3-6 days Grade II - combusti bullosa /vesiculosa/ ●Grade II A ●Red undersurface of blister ●Capillary refill intact ●Healing time 7-14 days ●No scar /hyperpigmantation ●Grade II ●Purple/white undersurface of blister ●No capillary refill ●Healing time 21 days ●Scar ● ● Grade III - combustio escharotica ●Damage to all layers of skin ●Pale, vax-like skin ●Necrosis ●No pain – destruction of nerves ●Scar ● Grade IV - carbonation ●Destruction of deep underlying tissues /fascias, muscles, bones/ Jackson´s burn model ●1. central zone of coagulation (irreversibile) ●2. zone of stasis (partialy reversibile) ●3. marginal zone of hyperaemia (reversible) Area of burns ●Estimation of burned area is vital for adequate treatment ●"Rule of hand (1%)" ●"Rule of 9" Inhalation thermal trauma ●Airways damage ●Swelling/necrosis ●Airways obstruction! ●CO exposure! ●ARDS ●Rapid therapy!!! ● ●Secure airways early How do I identify inhalation injury? Barrier function of skin ●Altered in Grade IIB and higher ●Tissue necrosis ●Swelling, hypoxia ●Bacterial contamination and infection ●Typically Pseudomonas aeruginosa ● ●Sterile dressing, TAT, ev. ATB Local damage ●LIRS... SIRS ●IL1,2, 6, 12, TNF alpha, Beta ●Histamine ●K+, myoglobin ●Pain ●Swelling ●Ischaemia ●Necrosis ●infection General answer ●SIRS ●Period of shock (24-14 days) ● ●Acute period of burn dissease ● ●Period of reconstruction ●Loss of plasma, hemoconcentration ●Hypovolemia, AKI ● ●Toxines resorbtion ●Hypoproteinemia ●Infection, Curling gastric ulcer, liver dysfunction etc. ● Treatment ●II. less than 10% ●III. Less than 2% ●II. 10-24% ●III. 2-10% ●II: over 25% ●III. Over 10% ●Special cases ●Burn unit ●Hospitalization ●traumacentre ●Ambulatory treatment Special cases ●Head and face ●Perineum + genital ●Hands ●Circular burns of chest, neck ●Inhalation thermal injury ●Children under 2yo, II. Type over 5% ●Geriatric patients ●electricity Treatment - goals ●Reduce local damage ●Prevent/treat general answer ●Prevent complications ●Reconstruct ● ●Proper treatment in proper time ●Technical help ●Pre-hospital help ●Acute care ●- symptomatic ●- supportive ●- surgical ●Reconstruction and rehabilitation Symptomatic ●Stop burning process ●Analgesia ●Local hypothermia ●/cooling/ ●Sterile dressing ●Prevention of hypothermy Supportive ●Fluid resuscitation ●Oxygenotherapy ●TAT ●ATB? ●Urinary output ●A,B,C,D Fluid resuscitation ●Min. 2 i.v. Lines ●ASAP ●Infants over 5% ●Children over 10% ●Adults over 15% ●Crystaloids, coloids? aminoacids ●Urinary output!!! ●Parkland formula ●RL 4ml x kg x % ●Brook formula 1:3 ●(crystaloids:coloids) ●0,5/1,5 ml x % x ...kg ●Evans formula 1:1 Surgical ●Urgent care: ●Escharotomy ●Fasciotomy ●On-demand/ planed: ●Necrectomy ●Wound treatment Necrectomy ●Surgical ●fascial vs. tangential ●Chemical ●40% benzoic acid ●40% salicyle acid ●Enzymatical - less ●colagenase ●protease Reparation, reconstructive surgery ●Plastic surgeons ●Dermo-epidermal graft ●Skin transplant ●Musculofascial flaps ●... ●Autotransplant ●Allotransplants ●Xenotransplants ●Synthetic materials ●(bovinne collagene, Synkrit...) Frostbites - congelationes ●Effect of low temperrature ●Not neccesary below 0 C´ ●Wind, wet ●Exposed skin ●Peripheral areas /acra/ ●General state of patient Types ●Frostnip ●Frostbite - 1st Degree - 2nd Degree - 3rd Degree - 4th Degree ●Non- freezing injury (Trench foot) ●Hypothermia ● Frostnip -mildest form of cold injury -Initial pain, pallor, numbness -reversibile, no tissue loss -Th: rewarming ●Frostbite ●1st Degree: hyperemia, swelling, no skin necrosis ●2nd Degree: clear blister formations, hyperemia, edema, partial-thickness skin necrosis ●3rd Degree: full-thickness and subcutaneous tissue necrosis, hemorrhage vesicle formation ●4th Degree: full-thickness skin necrosis + muscles, bones, gangrene ● Trenchfoot ●endothelial damage, stasis, vascular occlusion ●Long-term exposure to wet conditions, temperatures just above freezing point ●Soldiers, sailors, fishermen… ●Trenchfoot ●Cold and numb tissue /24hours/ - due to arterial vasospasm ●progressing to hyperemia, pain, hysestesia ●Edema, blisters, redness, ulcerations ●Local infection, cellulitis, gangrena ● Local and general answer ●Vasospasm ●Ischemia ●Swelling ●Necrosis ●Secondary complications ●Infections ●Sepsis ●Hypothermia - less than 36 C´ ●Mild - 32-35C´ ●Moderate – 30-32 C´ ●Severe- less than 30C´ ●Neurological problems ●Arytmia ●Cardiac arrest Treatment ●Exposure! ●Re-warm ●Local/circulating water 40C´/ (no dry heat, no rubbing!!!, pain management) ●Systematic – hot drinks, i.v. fluids ●Wound care ●Goal – prevent infection, preserve damaged tissue ●elevation, avoid opening clear blisters, imobilisation, TAT, ATB? ● Corrosion - chemical burns ●Exposure to acids, alkalies, petroleum products ●Acids - coagulation ●Alkalies – colliquation (deeper penetration ) ●Injury influenced by: - Type, amount, concentration, time of exposure ●Treatment: rapid removal, neutralization(?), irriigation, sterile dressing, TAT, ATB? Internal use of chemicals ●Accidental, suicidal ●Alkalies, acids / ●Hyperemia, flegmona, necrosis, ulcers, perforation… chroniicity - stenosis ●Dyspnoe, odynophagia, hoarseness, pain, laryngeal spasm, metabolic disorder ●GFS? PPI, NGT, irrigation, ATB, PEN ● ● Thank you