Nerve tissue Neurons Glial cells CNS: oligodendrocytes, astrocytes, ependymal cells, microglia PNS: satellite cells, Schwann´s cells Synapse Myelinization Hemato-encephalic barrier Cortex cerebri Cortex cerebri – pyramidal cells – multipolar neurons Cortex cerebri – pyramidal cells – multipolar neurons impregnation Cerebellum (impregnation) arbor vitae white matter gray matter Cerebellum – Purkinje cell stratum moleculare stratum granulosum Cerebellum - Nissl bodies in Purkinje cells (Nissl staining) GM WM somatomotoric multipolar neurons Medulla spinalis gray matter - somatomotoric multipolar neurons white matter myelinated axons Medulla spinalis axon hillock Nissl bodies Somatomotoric multipolar neuron – medulla spinalis Medulla spinalis – ependymal cells gray matter white matter Ganglion spinale (DRG) pseudounipolar neurons 13 Ganglion spinale (DRG) – pseudounipolar neuron satellite cells Schwann cells Vegetative ganglion – ganglion cells (multipolar neurons), satellite cells Peripheral nerve endoneurium perineurium epineurium myelinated axons nerve bundles Development of myelin sheath http://lecannabiculteur.free.fr/SITES/UNIV%20W.AUSTRALIA/mb140/CorePages/Nervous/Nervous.htm#CNS Peripheral nerve - myelin sheath - Schwann sheathnuclei of Schwann cells Peripheral nerve – longitudinal section node of Ranvier axons internodium (myelin segment) : 1-1.5 mm Myelin sheaths with nodes of Ranvier – peripheral nerve (OsO4) Axons with myelin and Schwann sheath nucleus of Schwann cell myelin sheath Synapse axon terminals motor end-plate muscle fibers Motor end-plates in motor unit Motor end-plates (localization of acetylcholinesterase) NEUROTRANSMITTERS Define footer – presentation title / department25 Hemato-encephalic barrier pericyte microglia Slides: Pyramidal cell (75, 76. Cortex cerebri) Purkinje cell (77. Cerebellum) Nissl substance (78. Cerebellum or 79. Medulla spinalis) Somatomotoric multipolar neuron (79. Medulla spinalis) Pseudounipolar neuron (81. Ganglion spinale) Peripheral nerve (84, 85. Peripheral nerve – cross section) Peripheral nerve (86, 87. Peripheral nerve – longitudinal section) Atlas EM: Neuron – cortex cerebri (3, 48), Purkinje neuron (49) Oligodendrocyte (50) Synapse (51) Hemato-encephalic barrier (52) Peripheral nerves (53, 54) NERVE TISSUE