11. Pharmacology of GIT

Activities in the lesson

1. Adverse effects of drugs on GIT

Make groups and discuss with your colleagues which drugs have characteristic adverse effects manifested in GIT. Describe which part of GIT is affected and how can we prevent the side effect.

2. Oropharynx

Find an answer to the riddle:

Mouth is the strange place to be. You stand on the beginning of the road, but for some things, it may be also the end, since they will not continue. On the other hand, some things want to stay here forever but they are not allowed to. What want to stay and what terminates here?


Now you will get more question on drugs acting in the oral cavity.

Antiseptics with answers

3. Oesophagus/stomach

Firstly, take a Kahoot on pharmacotherapy of gastroduodenal ulcers.

Kahoot

Download the file and try to sort information on antiemetics.

First aid kit with key

4. Liver/gall bladder

The teacher will ask you questions on the topics of hepatoprotectives, cholagogues and choleretics.

5. Intestines

Make pairs. One of you will be a physician the other is a patient suffering with diarrhea. The task for the physician is to find out the probable cause of the diarrhea and recommend the correct therapeutic measures. The roles will be changed in the second task. Now the patient comes with constipation. You can use a review of antidiarrhoeics and laxatives below.

Finally, think about drugs that can be used to treat flatulence.

Laxatives

Antidiarheals

6. Rectum

Similarly to oropharynx, suggest groups of drugs used in this part of GIT and give an example of drug that is available for the rectal administration.

7. Review

Suggest suitable pharmacotherapy for the following cases:

  1. Oncological patient suffering from opioid-induced constipation.
  2. A 7-year-old child with infectious diarrhea.
  3.  Patient with highly emetogenic chemotherapy.
  4. An 8-year-old child suffering from motion sickness.
  5. Patient with Meniere's disease.
  6. Prokinetic agent for the patient with Parkinson´s disease.
  7. Therapy of peptic ulcers in the stomach with positive Helicobacter pylori test.
  8. Drug for the therapy of radiolucent gallstones.
  9. Spasmolytic agent for biliary colic.
Case reports

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