Infectious Diseases II

Viral hepatitis A and E



VHA fecal-oral, VHE alimentary transmission in Europe
VHA - local outbreaks, VHE - sporadic cases
Asymptomatic or mild course (self-limiting disease)
Severe course - old or patients with underlying chronic liver disease
Fulminant hepatitis - cirrhotic patients 
Chronic VHE - solid organ transplant recipients, ribavirin treatment