1 Theoretical Bases of Clinical Medicine 2-3 Learning outcomes TBL LESSON: 09 Michaela Rámová – Liver and biliary tract disease [Martina Žižlavská] Upon completion of this instructional unit, the student will be able to: • interpret standard liver tests and explain their significance in the diagnosis of liver diseases • define and categorize jaundice, its clinical symptoms, and distinguish between types based on clinical laboratory tests • explain the mechanism of liver damage caused by alcohol and the influence of alcohol on drug metabolism • explain the mechanism of liver damage caused by paracetamol and the method of treating paracetamol overdose • discuss the correct choice of laboratory tests in a given clinical context • discuss laboratory results in the given clinical context, recognize clinically significant and life-threatening values • discuss the indication of paraclinical examinations and their appropriate timing in the given clinical context • explain the treatment procedure for acute gastrointestinal bleeding • discuss the course of resuscitation in a hospital setting, cooperation with the ICU team • discuss indications for performing a pathological-anatomical autopsy and other types of autopsies • explain the classification of liver failure and possible treatment approaches • discuss possible causes of consciousness disorders in the given clinical context • apply knowledge in the treatment of hypoglycemia