1 Theoretical Bases of Clinical Medicine 2-3 Learning outcomes TBL LESSON 12: Hutárkovi – Food poisoning, anaphylactic shock [Hana Harazim] Upon completion of this instructional unit, the student will be able to: • explain the clinical signs of anaphylaxis based on pathophysiological mechanisms • compare the pathophysiological mechanisms and clinical manifestations of IgE and non-IgE mediated type 1 hypersensitivity reactions • recognize symptoms of anaphylaxis/allergic reaction from the patient's history and clinical examination • confirm the diagnosis of anaphylaxis/allergic reaction using laboratory tests • compile, based on pathophysiology knowledge, a list of drug groups applicable for the treatment of anaphylaxis/allergic reactions • list the routes of adrenaline application in anaphylaxis, including recommended dosing, and demonstrate the use of an adrenaline auto-injector in urgent care • identify infectious diarrheal diseases based on collected history and results of microbiological tests • enumerate the pathophysiological mechanisms of diarrhea development • propose suitable hospital and outpatient procedures for the causal and symptomatic treatment of diarrhea • assess the contribution of epidemiological-hygienic investigation of infectious diarrheal diseases