IODINE Michaela KrMichaela Kráállííkovkováá, MD, MD DepartmentDepartment of Biochemistryof Biochemistry FacultyFaculty ofof MedicineMedicine Masaryk UniversityMasaryk University MetabolismMetabolism andand significancesignificance * RDI = 150-220 g * iodine supplementation of salt, soft food * resorption as Iˇˇ extractedextracted fromfrom bloodblood circulationcirculation byby thyroidthyroid folicullarfolicullar cellscells,, oxidizedoxidized toto II22 TT44 a Ta T33 synthesissynthesis DeficiDeficiencyency * endemic goiter * inborn hypothyroidism screening of neonates * urinary excretion * normal value >100g/l * therapy: I 100 g/d