including transphosphorylation reactions involving
central to cellular energy metabolism and the
macromolecules synthesis
stabilisation of cell membranes
needed for production of bone matrix, blood coagulation
protects from urinary concrements production
Clinical symptoms of hvDermagnesemi
peripheral vasodilatation —► hypotension
depression of cardiac conduction system —► brady arrhythmias
depression of the CNS
curarelike effect on neuromuscular junctions —> muscle
weekness
yocardial ischemi
As a co-enzyme participates in lipids, steroids, saccharides and AA metabolism, NA degradation, ATP involved reactions, that is reactions of energy transport needed for muscle contraction.
physiological antagonist of Ca2+
It protects the myocardial cells from excessive influx of Ca2+ and supports the stripping ofCa2*.
Mechanism of influence of hypomagnesemia on myocardial ischemia:
I Mg2+ —► j Ca2+ influx —► vasoconstriction —► aggravation of myocardial ischemia
nd myocardial ischemi
control group                                0.75 ± 0.04 nimol/1
IHD or cardiomyopathy
- with diuretics (t urinary loss of Mg2+) 0.64 ± 0.08 ill m 01/1
- without diuretics                             0.68 ± 0.09 in m o 1/1
Control Mg2+/S in patients with cardiovascular dis.
g administration in these patients is helpfi