Pharmacology

                               General medicine - practical courses

                                       Autumn semester 2014

SEMINARS
Day 1 (Mon)
Introduction, instructions. Distribution of co-talks.

1/ANALGESICS.
Opioid analgesics. Pharmacotherapy of pain. Opioid addiction therapy. Prescription and practical
use of analgesic preparations.
2/NON-STEROIDAL ANTIINFLAMMATORY DRUGS, DRUGS USED IN GOUT, ANTIPYRETICS.
Mechanisms of action and classification of anti-inflammatory and anti- rheumatic drugs (NSAIDs and
the 2nd-line agents). Drugs used in therapy of gout.
Getting ready for the next lesson: Central neurotransmitters and sites of drug effects in CNS.
Basic psychical functions.
Revision: CNS neurotransmitters and receptors, Autonomic nervous system – catecholamines, atropine.
Myorelaxants.
Day 2 (Tue)
3/PSYCHOTROPIC DRUGS.
Classification and terminology of psychotropics. Review of their mechanisms of action. Pharmacology
of anxiolytics and hypnosedatives. Mechanism of action of benzodiazepines. Prescription of
hypnosedatives and psychostimulants.
Co-talks.
4/GENERAL AND LOCAL ANAESTHETICS
Combined and balanced anaesthesia. Signs and stages of general anaesthesia. Inhaled and injected
anaesthetics - classification and characteristics. Review of drugs used in premedication.
Co-talks.
Getting ready for the next lesson: Structure of bacterial cell, basis of antimicrobial therapy.

Day 3 (Wed)
5/ANTIMICROBIAL AGENTS I.
Classification, mechanisms of action, combinations of antibiotics and chemotherapeutics.
Co-talks.
6/ANTIMICROBIAL AGENTS II., CHEMOTHERAPEUTICS, THERAPY OF INFECTIOUS DIARRHEAS AND UROINFECTIONS.
Drugs acting in intestinal and urinary infections.
Co-talks.
Getting ready for the next lesson: Allergic reactions – causes and mechamisms. Revision of PNS
pharmacology - β[2] mimetics, parasympatholytics. Glucocorticoids.
Day 4 (Thu)
REVISING TEST I (Overhead-test with subsequent discussion) Lesson 1 – 6.
7/CASE REPORTS I.
Selected case reports on drugs from previous lessons. (Including Pharmacology I lessons)
8/H[1] ANTIHISTAMINES, ANTIASTHMATICS.
Classification and clinical use of H[1] antihistamines. Pathophysiology of bronchial asthma, sites
and mechanisms of action of antiasthma drugs. Prescription of antitussives, expectorants,
antiasthmatics.
Co-talks.
Getting ready for the next lesson: Revision of praescription terminology, pathophysiology of
gastric ulcers
Day 5 (Fri)
PRESCRIPTION TEST: DRUGS ACTING IN CNS, ATB, LOCAL ANAESTHETICS,H[1] ANTIHISTAMINES,
ANTIASTHMATICS.
9/DRUGS USED IN ULCER DISEASE, ANTIEMETICS
Classification, mechanisms of action and clinical use of drugs in therapy of peptic ulcer and
vomiting.
Co-talks.
10/ANTICOAGULANTS AND THROMBOLYTICS.
Fibrinolytics, haemostatics, therapy of haemopoietic disorders.
Co-talks.
Getting ready for the next lesson: Physiology of blood pressure regulation. Revision of PNS
pharmacology- α[1] sympatholytics, α[2] sympathomimetics, β sympatholytics.
Day 6 (Mon)
11/HYPOLIPIDEMICS, THERAPY OF OBESITY.
Therapy of hyperlipoproteinaemia and hypercholesterolaemia, review of drugs and their mechanism of
action.
Co-talks.
12/ANTIHYPERTENSIVE AGENTS.
Introduction, classification, diuretics, beta blockers, ACE inhibitors, Ca^2+ blockers.
Co-talks.
Getting ready for the next lesson: Revision of lessons from lessons 7-12; patophysiology of cancer
disease.
Day 7 (Tue)
REVISING TEST II (Overhead-test with subsequent discussion). Lessons 7 - 12.
13/CASE REPORTS II.
Selected case reports on drugs from previous lessons. (Including Pharmacology I lessons)
14/PHARMACOLOGY OF ANTICANCER DRUGS.
Classification, mechanisms of action, side effects.
Getting ready for the next lesson: Revision of prescription of drug dosage forms for external use.
Day 8 (Wed)
FINAL PRESCRIPTION TEST (includes dermatology).
15/REVIEW OF DRUGS USED IN DERMATOLOGY AND OTORINOLANRYNGOLOGY.
CREDITS.




                          MUDr. Regina Demlová, Ph.D.


           Head of the Dpt. of Phrarmacology, LF MU