Tutorial II: autumn semester 2015/2016 Group No. 30 10/5/2015 13:30 - 15:10 "Campus,Department of Physiology, room 207" Group No. 33 10/6/2015 16:00 - 17:40 "Campus,Department of Physiology, library" Group No. 31 10/7/2015 12:30 - 14:10 "Campus,Department of Physiology,room207" Group No. 32 10/8/2015 14:00 - 15:40 "Campus,Department of Physiology, room 207" Group No. 37 10/13/2015 16:00 - 17:40 "Campus,Department of Physiology, library" Group No. 34 10/14/2015 12:30 - 14:10 "Campus,Department of Physiology,room207" Group No. 35 10/26/2015 13:30 - 15:10 "Campus,Department of Physiology, room 207" Group No. 36 10/26/2015 16:00 - 17:40 "Campus,Department of Physiology,room 207" "The tutorial takes place in the Department of Physiology, building A 20, " "Campus, , Kamenice 5, Brno-Bohunice" "The tutorial will be held by Associate Professor P. Babula, Ph.D." Program: Hemostasis Circulation and hemostasis Blood vessels tone and its importance for blood flow. Characteristics of blood flow in vessels. Endothelial function. Local reaction of vessels after vessel wall damage. Mechanisms of vasoconstriction and vasodilation. Circulating vasoactive molecules. Primary hemostasis and platelets "Thrombopoesis, number, morphology, structure and shape " "(membrane, glycocalyx, granules) of thrombocytes." "Thrombocyte function - 3A (adhesion, activation, aggregation)." Hemocoagulation "Protein and cellular model of blood clotting. Overview of the coagulation factors, their synthesis" and function. Intrincis and extrinsic activation of coagulation cascade. Regulation of hemostasis "Humoral regulation of hemostasis. Anticoagulation, fibrinolysis, thrombolysis." Non-humoral regulation of hemostasis. Clinical applications "INR, anti-Xa, anticoagulants, fV-Leiden mutation." All students are obliged to read the theory prior to the tutorial. "The tutorials are obligatory, the presence is the condition for obtaining the credit. " All students are allowed to substitute only one tutorial during one semester - those who will have more than one absence will not obtain the credit from tutorials. "doc. PharmDr. Petr Babula, Ph.D." Head of the Department of Physiology