1 Hospital hygiene Kolářová M., Spring 2016 2 Chain of Infection Causative agent - bacteria, viruses, fungi, parasites, priony Source of infection The ende incubation period,, illness carriers Mode of transmission -direct -indirect Susceptible host Infection 3 Chain of Infection in Hospital Conditions Source of Infection The Transmission Susceptibility pacient pacient pacient Health worker Health worker pacient 4 EPIDEMIC PROCESS IN THE HOSPITAL ENVIRONMENT SOURCES OF INFECTION MODE OF TRANSMISSION trough biological material of patients or contaminated surfaces or equipments SUSCEPTIBLE HOST 5 Biological materials – their infectivity 1. Causative agens in blood, derivates from blood, plasma VHB, VHC, VHA (short in the blood), HIV, CMV, rarely EBV, virus of morbilli (viremie), kandidy-kandidémie, malárie - (plasmodia can survive in fresh plasma 3 – 5oC - 14 days), Toxoplasma gondii - (can survive in blood - 56 days) 6 Biological materials – their infectivity 2. Causative agens in droplets Adenovirus, coronaviruses, enteroviruses, herpes virus, myxovirus (influenzae), paramyxovirus, RSV, rhinovirus, Stafylococcus, Streptococcus spp., Meningococcus spp., Haemophilus Influenzae, Neisseria meningitis, Bordetella pertussis, Bordetella parapertussis, Mycoplasma pneumoniae, Pneumocystis carinii, Kandidy…. 7 Biological materials – their infectivity 3. Causative agents in stool Enteroviry (VHA, poliomyelitis), VHE, coxsackie viry, Adenoviry, Enterobactericeae (E.coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus spp., Citrobacter, Enterobacter, Serratia apod) Listeria monocytogenes, Clostridium perfringens, Clostridium tetani, Pneumocystis carinii 8 Biological materials – their infectivity Causative agens in: 4. URINE Virus of measles, parotitis, CMV, VHB, papovavirus, Listeria monocytogenes, Candidae 5. LIQUOR HIV, different causative agents of meningitid 6. Salive VHB, HIV, CMV, EBV, herpes virus hominis typ 1,2, virus of measles, rubellla 9 Biological materials – their infectivity 7. TEARS, EYE - SECRET VHB, HIV, adenoviruses, Enterovirus typ 70, Coxsackie A 24, Staphylococcus aureus, hemophfilus, pneumokoky, moraxely, chlamydie 8. VAGINA AND CERVIX - SECRET HIV, VHB, rare VHC, herpes virus hominis typ 1,2, Streptococcus agalactiae, Neisseria gonorrhoea, Haemophilus Ducreyi, Treponema pallidum, Trichomonas vaginalis, Chlamydia lymfogranulomatosis, Chlamydia trachomatis 9. EJACULAT VHB, HIV, rare VHC, CMV, 10 Chain of Infection in Hospital Conditions SOURCE OF INFECTION MODE OF TRANSMISSION SUSCEPTIBLE ORGANISM HANDWASHING, DISINFECTION OF HANDS LINEN WASING, CLEANING …….., ……… DISINFECTION STERILIZATION 11 Construction, technical conditions Mikroclimate Laundry Food, water Bathroom, WC Cleaning, transport Specific entrance -medical devices Emision Liquid waste Chemical waste Radioactive waste Komunální odpady Medical waste incl.sharp Care for a patients People 12 PACIENT LINEN WASHING, ……….., DISINFECTION, STERILIZATION Wastes A) Tools for one use B) Reuseable tools 13 14 15 Staphylococcus aureus in a patient who has a Hickman catheter. The extending cellulitis (maximum extent shown by black marker pen line) has responded but the local tunnel infection persists and mandates line removal. 16 Catheter exit site infection in a patient with central venous catheterization through the jugular vein. 17 Diffuse skin involvement with petechial lesions in a patient with Staphylococcus aureus bacteremia, endocarditis and acute aortic insufficiency. 18 An acutely infected knee replacement. The site was washed out but the infection failed to resolve. At re-operation the implant was found to be loose and it needed to be removed. Staphylococcus aureus was grown from deep specimens. 19 20 21 22 23 24 Municipial waste – syringes with blood !!! 25 Municipial waste – test tubes with blood !!! 26 Municipial waste – ………. !!! 27 Sorted waste – glasses with syringes and needles (after using) !!!! 28 Sorted waste – glasses with giving set (after using) !!!! 29 The rest medicaments in the glasses = hazardous waste !!! 30 The bag with blood in the transparent sack !!!! (must be black and nontransparent and fat (0,2 mm) with symbol „Biological Risk)