Treatment in dermatology Topical-Use-of-Vitamin-A Výsledek obrázku pro topical treatment eczema psoriasis-oral-medication-200 Treatment in dermatology •Drugs - topical • - systemic •Surgery •Physical therapy • - phototherapy • - cryotherapy • - electrotherapy • - laser •Balneotherapy, • thalassotherapy • • deadsea paste Lotion Shake lotion powder Emulsion w/o ointment o/w cream, lotion liquid Fat/oil Fatty ointment Topical therapy •Correct diagnosis (tinea incognita, eczema herpeticatum) • •Stage of the disease – acute, subacute, chronic • •Site of the body – face, palms, soles, scalp, intertriginous areas image48 Topical treatment in dermatology •ATB – fusidic acid, mupirocin •Antifungal drugs –ciclopiroxolamin, miconazol, terbinafin, clotrimazol •Virostatics – acyclovir •Parasiticides – permethrin, •Retinoids – adapalene, tretinoin •Vitamin D derivates – tacalcitol, calcipotriol •Immunomodulators – imiquimod •Cytostatics – podophylotoxin, 5- fluorouracil • • daivonex •Emollients - moisturizers •Antiseptics - povidone iodine, chlorhexidin, kalium permanganate, polyhexanide, bleach (sodium hypochlorite) •Astringents •Keratolytics - salicylic acid, urea •Coal tar •Antimicrobial substances – chloroxine •Immunosupressives – tacrolimus •Corticosteroids Topical treatment formulations •Aqueous solutions •Baths •Wet dressing •Alcoholic solutions – tinctures •Shampoos •Sprays •Powders •Lotions •Gels •Pastes •Oils •Ointments and emulsions – fatty ointments x creams • Výsledek obrázku pro coal tar psoriasis Topical treatment •Antiperspirants •Depilatory substances •Sunscreens •Depigmenting drugs •Camouflage •Varnishes •Protective ointments •Antiinflammatory drugs •Transdermal patches photo-84483-dermablend • Topical corticosteroids •Antiinflammatory effect (eczema, allergic reactions) •Vasoconstriction •Reduction of oedema •Reduction of itch •Antiproliferative effect (autoimmune diseases) •Antiscarring effect Blanching_0 Corticosteroids - potency •Class IV] •Very potent (up to 600 times as potent as hydrocortisone) •Clobetasol propionate (Dermovate Cream/Ointment, Exel Cream) • •Class III •Potent (50-100 times as potent as hydrocortisone) •Betamethasone valerate (Beta Cream/Ointment/Scalp Application, Betnovate Lotion/C Cream/C Ointment, Daivobet 50/500 Ointment, Fucicort) •Betamethasone dipropionate (Diprosone Cream/Ointment, Diprovate Cream) •Hydrocortisone 17-butyrate (Locoid C/Cream/Crelo Topical Emulsion/Lipocream/Ointment/Scalp Lotion) •Mometasone furoate (Elocon Cream/Lotion/Ointment) •Methylprednisolone aceponate (Advantan Cream/Ointment) • •Class II •Moderate (2-25 times as potent as hydrocortisone) •Triamcinolone acetonide (Aristocort Cream/Ointment, Viaderm KC Cream/Ointment, Kenacomb Ointment) • •Class I •Mild •Hydrocortisone 0.5-2.5% (DermAid Cream/Soft Cream, DP Lotion-HC 1%, Skincalm, Lemnis Fatty Cream HC, Pimafucort Cream/Ointment) • Side effects of corticosteroids •Tachyphylaxis •Rebound phenomenon •Atrophy – striae distensae •Interference with wound healing •Vasoconstriction, telangiectasia •Perioral rosacea like dermatitis •Hypertrichosis •Immunosuppression • • • ANd9GcTarNBTkiUQpaEGbUmm4Way5zCfD_9f9Zf2inv3q_SCFXMNyaGh 081112-maggot-jar-02 Dead-Sea-Mineral-Mud Výsledek obrázku pro mepitel one Výsledek obrázku pro topical treatment eczema