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Pathophysiology - practicals
Autumn/2020 – General Medicine (en)
Department of Pathophysiology FoM MU
UKB Kamenice 5/A18 – seminar room I/112 (ground floor)
Mondays (10:00 – 12:30); Mondays & Tuesdays & Thursdays (13:00 – 15:30)
week date topic teachers
1 5.10. 6.10. 8.10.
Introduction, health & safety in the lab. Principles and
demonstration of peripheral blood flow examination using
ultrasonography. Training of techniques for experimental
practice
as scheduled
2 12.10. 13.10. 15.10.
Interindividual variability (tutorial). Training of techniques for
experimental practice
as scheduled
3 19.10. 20.10. 22.10.
Principles and ethics of experimental use of laboratory animals,
basic surgical skills, general principles of work with lab. animals
& explorative laparotomy
as scheduled
4 26.10. 27.10. 29.10.
Principles of ECG analysis, demonstration of selected
pathological ECG patterns
Dr. J. Máchal, Ph.D./
as scheduled
5 2.11. 3.11. 5.11.
Conductive disorders (seminar), ECG monitoring of exp.
induced arrhythmias in lab. animal as scheduled
6 9.11. 10.11. 12.11.
Exp. induced renal ischemia (part 1) Mgr. Lukáš Pácal, Ph.D.;
Ing. Hana Polanská, Ph.D.
7 16.11. 17.11. 19.11. Exp. induced changes in blood flow in the splanchnic region of
the experimental animal
as scheduled
8 23.11. 24.11. 26.11.
Pathophysiology of ventilation disorders and pulmonary gas
exchange – spirometry.
as scheduled
9 30.11. 1.12. 3.12.
Exp. induced renal ischemia – detection of renal renin
expression (part 2)
Mgr. Lukáš Pácal, Ph.D.;
Ing. Hana Polanská, Ph.D.
10 7.12. 8.12. 10.12.
Exp. induced acute renal insufficiency in lab. animal –
measurement of GFR based on kinetics of renal inulin excretion
Mgr. Lukáš Pácal, Ph.D.;
Mgr. Lucie Válková
11 14.12. 15.12. 17.12.
Cell cycle, oncogenes and suppressor genes, cancer
development. (tutorial)
Dr. J. Gumulec, Ph.D.;
Dr. Jan Balvan, Ph.D.
12 4.1. 5.1. 7.1.
Genetic susceptibility to disease – monogenic vs. complex
diseases (tutorial) as scheduled
13 11.1. 12.1. 14.1.
Statistical analysis of experiments (introduction). Dr. Michal Jurajda, Ph.D.;
Dr. Jan Máchal, Ph.D.
14 18.1. 19.1. 21.1. Tests, credits as scheduled
Literatura:
1. Kaňková K, Pácal L, Jurajda M, Izakovičová-Hollá L, Bienertová-Vašků J, Masařík M, Vašků A: Pathophysiology
practicals for General Medicine and Dental Medicine courses. Portal of MU’s Faculty of Medicine [online] 2008-12-15,
last modif. 2008-12-16 [cit. 2008-12-17]. Available from http://portal.med.muni.cz/article-477-pathophysiology-
practicals-for-general-medicine-and-dental-medicine-courses.html