Organizational instructions

Atherosclerosis. Angiology, pulse wave, LI. Principles and demonstration of peripheral blood flow examination using ultrasonography.

Principles and ethics of experimental use of laboratory animals. Interindividual variability (tutorial). Training of techniques for experimental practice. Explorative laparotomy.

Essential hypertension (tutorial), resting and ambulatory blood pressure (and heart rate) measurements, postural changes, effect of isometric and aerobic exercise.

Principles of ECG analysis, demonstration of selected pathological ECG patterns.

Exp. induced acute renal insufficiency in lab. animal – measurement of GFR based on kinetics of renal inulin excretion

Genetic susceptibility to disease – monogenic vs. complex diseases. Pharmacogenetics.

Pathophysiology of respiratory disorders – introduction. Obstructive and restrictive disease. Spirometry

Exp. induced renal ischemia (part 1)

Pathophysiology of ventilation disorders and pulmonary gas exchange. Pathophysiological principles of oxygenotherapy and mechanical ventilation.

Cell cycle, oncogenes and suppressor genes, cancer development.

Statistical analysis of experiments (introduction).

Acid-base balance (seminar)

Credit test