Non-invasive methods of blood pressure measurement Arterial blood pressure curve SBP Systolic blood pressure area above MAP area under MAP DBP Diastolic blood pressure MAP Mean arterial pressure inter-beat interval Mean arterial pressure (MAP) : mean value of blood pressure in the inter-beat interval (IBI) •area under MAP = area above MAP •approximation: MAP » DBP + 1/3 PP (PP = SBP – DBP) • PP pulse pressure Blood pressure (BP): pressure on the vascular wall (a continual variable) Definition: SBP - maximum of BP in the inter-beat interval DBP – minimum of BP in the inter-beat interval Attention: Values of SBP and DBP varies in different parts of cardiovascular system! MAP is a function of cardiac output and total peripheral resistance •SBP is given mainly by CO •DBP is given mainly by TPR Mean arterial pressure (MAP) Total peripheral resistance (TPR) Heart rate (HR) Stroke volume (SV) = * * Cardiac output (CO) Methods of the arterial blood pressure measurement 24-hour blood pressure monitoring Palpatory (sphygmomanometer) Auscultatory (sphygmomanometer, stethoscope) Oscillometric Photoplethysmographic (volume-clamp method, Peňáz) Laminar / turbulent flow, Korotkoff sounds Reynolds number Re: predicts the transition from laminar to turbulent flow v: velocity of blood flow S: area of vascular lumen (p.r2) r: density of blood h: viscosity of blood (lower in anemias) S1 < S2 , v1≈ v2 → Re1 < Re2 → turbulent flow laminar flow Re < 2000 turbulent flow Re > 3000 r1 r2 cuff a. brachialis laminar flow turbulent flow Re1 Re2 v1 v2 right behind the narrowing of the artery: Korotkoff sounds (auscultatory method) Continually measured BP Pressure in the cuff Pressure oscillations in the cuff (Oscillometric method) SBP DBP SBP MAP DBP Blood flow in the artery Principles of blood pressure measurement •Patient is sitting and resting for a few minutes before the measurement. •Only validated measuring equipment must be used. •At least two measurements have to be performer, in the course of 1–2 minutes. •Use cuff of standard size (12–13 cm width and 35 cm length); smaller and bigger cuffs must however be available for patients with smaller or bigger arms, respectively. •Cuff must always be at the level of heart of examined person. •Pressure in the cuff must be decreased slowly: 2mmHg/s. During BP measurement, following rules must be observed: 24-hour blood pressure monitoring BP decrease during night: 10 - 15% 8 9 11 10 12 13 14 16 15 17 18 19 21 20 22 23 24 2 1 3 4 5 7 6 120 140 100 80 60 [mmHg] SBP DBP Heart rate waking sleeping Blood pressure hours Photoplethysmography Control system Constant finger volume pressure Control system: Correction of the pressure in the finger cuff according to the arterial lumen changes. Aim: maintaining of constant arterial lumen through pressure changes in the cuff. cuff SBP DBP Variability of circulatory parameters time (s) frequency (Hz) T=50 s T=10 s T=3 s a=0.5 a=0.3 a=0.2 period T amplitude a frequency f = 1/T f = 1/3 = 0.33 Hz f = 1/10 = 0.1 Hz f = 1/50 = 0.02 Hz 0.5 0.2 0.3 + + = + + = 0.5 0.2 0.3 0.33 0.02 0.1 f = 0,02 Hz f = 0,1 Hz f = 0,33 Hz Spectrum Frequency domain Time domain Baroreflex •Inotropic •Chronotropic •Dromotropic •Batmotropic Aferent pathway Parasympathetic pathway Sympathetic pathway BP=HR x SV x R R HR BP=HR x SV x R Valsalva maneuver