1
Teoretical Base of Clinical Medicine 2-3
Learning outcomes
TBL LESSON: 01 Angela Robinson - Coagulation disorders - pulmonary embolism [Tamara Skříšovská]
Upon completion of this learning unit, students will be able to:
• describe the extrinsic and intrinsic pathways of the coagulation cascade
• provide an overview of the most common inherited and acquired coagulation disorders
• explain genetic and environmental factors predisposing to thrombosis
• describe coagulation tests and interpret their results accurately
• define an embolus and distinguish between different types, such as air, fat, and malignant tissue,
among others
• relate the clinical presentation of pulmonary embolism, including its symptoms and underlying
pathophysiology
• explain the principles of diagnosing pulmonary embolism
• compare the indications, mechanisms of action, adverse effects, and roles in therapy of available
treatment modalities for pulmonary embolism
• interpret the sensitivity and specificity of clinical tests and their practical applications