DIGESTIVE SYSTEM 3
➢ Big salivary glands parotid gland
submandibular gl.
sublingual gl.
➢ Liver
➢ Gallbladder
➢ Pancreas
Salivary glands - schema
secretory portion
serous acini
mucous tubules
mixed /serous demilunes
of Gianuzzi/
+ myoepithelial cells
duct system
intercalated ducts
intralobular /striated/
ducts
interlobular and
interlobar ducts
main excretory duct
Glandular parenchyma
Secretory portion of salivary
glands
• serous acini
• mucous tubules
• mixed (serous
demilunes of
Gianuzzi)
Parotid gland
Compound acinar serous gl.
ducts – intercaleted,striated, interlobular,
excretory ducts
Adipose tissue
serous acini
adipose cell
striated duct
Submandibular gland
Compound tubuloacinar mixed gl.
Submandibular gland
Serous demilune
Serous acini
Mucous tubules
Sublingual gland
Compound tubuloacinar mixed gl.
Classic liver lobule
• Shape – polygonal ( polyhedral )
• Central vein
• Hepatocytes in interconnected plates
• Liver sinusoids
• Bile canaliculus
2D cross section 3D
1 – 2 mm
Portal space
Classic liver
lobule
Central vein
trias hepatis /Glissonova triáda/
Central vein
Liver sinusoid
Liver plates
Játra – portální triáda
Bile duct
Portal
vein
Hepatic
artery
Žlučník /vesica fellea/
Liver parenchyme
Adventitia
Folds of
mucosa
Mucous coat
T. muscularis
externa
Serous
layer
Gallbladder with mucus
Vesica fellea – slizniční řasy
simple columnar epithelium
lamina propria mucosae
Pancreas - HE, 10x
Interlobular duct
Serous
acinus
Septum
Islets of Langerhans
Pancreas – serous acinus, HE , 10x
Acinus
Centroacinar cells
Acinar cells
Pancreas, He, 10x
Intralobular
duct
Acinar cells
Pancreas, HE, 40x
Sinusoids
Islets of Langerhans
3.
Digestive system - III
Slides:
8. Glandula parotis (HE)
9. Glandula submandibularis (HE)
10. Glandula sublingualis (HE)
20. Hepar (HE)
21. Hepar (AZAN)
22. Vesica fellea (HE)
23. Pancreas (HE)
Atlas EM:
Bile canaliculus 9
Hepar – Kupffer cells 67
Pancreas – Islets of Langerhans 66
Development of pancreas 85
duodenal loop
is formed
liver
Pancreas – passes into dorsal mesoduodenum and mesogastrium by proliferation of
endoderm of duodenal loop;
During rotation of stomach and duodenum – duodenum + pancreas are situated
retroperitoneally
Lien – arises by proliferation of mesoderm cells in dorsal mesogastrium, which is
transformed into lig. gastrolienalis and lig. lienorenalis.
Spleen is intraperitoneal organ, its surface is covered by mesothelium.
The diaphragm originates from:
1. septum transversum (mesoderm mass)
2. plicae pleuroperitoneales
3. mesooesophageum dorsale
4. dorsolateral wall of the body
Development of diaphragm
Week 5 month 4