Oncological disease of the colon and rectum Teaching lesson 3 Written by: Zdeňka Smejkalová, Jitka Slaná Reissmannová Oncological disease of the colon and rectum •The word colon comes from Latin •Functions of the colon •Absorption of water and mineral substances •Thickening of the intestinal content •Excretion of indigestible residues • •Joint identification of colorectal carcinoma • Structure of the digestive system (1) Occurrence of colorectal cancer (2) Colon cancer is the third most frequent neoplastic disease! (3) Risk factors and symptoms •Risk factors •Age (age group over 50 years) •Hereditary predispositions •Intestinal polyps •Chronic inflammatory diseases •Inadequate food structure •Decreased physical activity •Excessive intake of alcohol •Smoking • •Symptoms •Long-term change in intestinal activity •Bleeding from the rectum or blood in the stool •Diarrhoea, constipation, feeling of insufficient emptying •Abdominal discomfort – feeling of fullness, flatulence, abdominal pain •Unintentional weight loss •Nausea, lack of appetite, fatigue, weakness • In case of any doubt or symptoms a physician must be consulted! Primary and secondary prevention •Primary prevention •Limited intake of energy-rich food •Limited food preparation at high temperatures •Sufficient intake of fibre, fruit and vegetables •Increased physical activity •Lower consumption of alcohol, non-smoking •Secondary prevention •Colorectal cancer screening •FOBT (faecal occult blood test) •50–54 years, once a year •Over 55 years, once every 2 years •Video •Colonoscopy •Over 55 years, once every 10 years •Video • • References •Jaké je mé riziko onemocnění? Screening kolorektálního karcinomu [online]. Brno: Masarykova univerzita, 2018. 12. 1. 2015 [cit. 2018-05-03]. Retrieved from: http://www.kolorektum.cz/index.php?pg=pro-verejnost--kolorektalni-karcinom--riziko-onemocneni •Jaké jsou příznaky onemocnění? Screening kolorektálního karcinomu [online]. Brno: Masarykova univerzita, 2018. 12. 1. 2015 [cit. 2018-05-03]. Retrieved from: http://www.kolorektum.cz/index.php?pg=pro-verejnost--kolorektalni-karcinom--priznaky-onemocneni •MACHOVÁ, Jitka. Biologie člověka pro učitele. Second edition. Praha: Univerzita Karlova v Praze, nakladatelství Karolinum, 2016. ISBN 978-80-246-3357-2. •Figures: •(1): Činnost trávicí soustavy. SlidePlayer [online]. c2019 [cit. 2019-03-24]. Retrieved from: https://slideplayer.cz/slide/11721318/ •(2), (3): Novotvary 2015 ČR [online]. Praha: Ústav zdravotnických informací a statistik ČR, 2015. [cit. 30/04/2018]. Retrieved from: http://www.uzis.cz/publikace/novotvary-2015 •