Medicinal Chemistry: Definition and history. Drug nomenclature.

Physico-chemical properties which influence drugs' activity. QSAR.

Structure features that influence drug action

Structure modification - homology, isomery, isostery

Drugs research and development. Good Manufacturing Practice

Drug biotransformation

Adrenergic receptor antagonists

Prodrugs. Weak analgesics, antipyretics, non-steroidal anti-inflammatory drugs

Strong analgesics - anodyns.

General anethetics. Muscle Relaxants. Local anesthetics.

Anxiolytics. Antipsychotics.

Antidepressants. Cognitive enhancers, stimulants, hallucinogens.

Sedatives. Hypnotics. Antiepileptics. Anticonvulsants. Vomitics. Antiemetics.