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Medicinal Chemistry I - lectures

Interaktivní osnova

Medicinal Chemistry I - lectures

General and local anesthetics. Muscle relaxants.

General anesthetics

Local anesthetics

Muscle relaxants

Předchozí

Medicinal Chemistry I - lectures
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  Introduction to the discipline. History of medicinal chemistry, nomenclature of drugs.
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  Physico-chemical descriptors and biological activity. Structure- Activity-Relationships. Structure optimization. An introduction to Quantitative Structure-Activity Relationships (QSAR).
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  Structure modification
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  General aspects of drug metabolism.
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  Prodrugs. Structure features that influence drug activity.
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  Adrenergic receptor agonists
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  Weak analgesics and non-steroidal anti-inflammatory drugs (NSADIs).
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  Strong or opioid analgesics. Endogenous opioids. Opioid receptors antagonists.
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  Adrenergic receptor antagonists
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  Research and development, Legislational requirements, GMP
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  General and local anesthetics. Muscle relaxants.
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  Antipsychotics. Anxiolytics.
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  CNS agents: antidepressants, stimulants, cognitive enhancers, psychotomimetics – hallucinogens.
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  CNS agents: sedatives, hypnotics. Anticonvulsants, antiepileptics. Emetics, antivomitics, antikinetics.

Operace

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