Thyroid hormones



                                         Thyroid hormones



                                   Effects of thyroid disruption



                                   Effects of thyroid disruption



                                         Thyroid hormones



                                         Thyroid hormones



                                      Pituitary-thyroid axis



                                    Enzymes involved in thyroid

                                            metabolism



                                        Mechanism of action



                                     Thyroid binding proteins



                                       Competitive binding to

                                      thyroid binding proteins



                                     Competitive binding to TR



                                    Accelerated depletion of TH



                                        In vivo assessment



                                        In vitro assessment