RNDr. Zdeňka Malá


Contribution to the theory and practice of capillary zone electrophoresis


The lecture describes the results of theoretical and experimental studies of electromigration
effects induced by the sample during the electrophoresis procedure. The methods used in our
investigation were theoretical calculations, computer simulations and experimental verification.
Example results are presented to show how the migration of the time-dependent concentration
profiles of the all system components and the creation of the various zone boundaries influence the
efficiency, sensitivity and reproducibility of the separations.