Organometallic compounds
Nomenclature
the polarisation depends upon the character of the metal
methylsodium
butyllithium
tetraethylplumbium
ethylmethylcadmium
phenyllithium
methylmagnesiumbromid

Organometallic compounds
reactivity of the compound depends upon the quality of the metal – its position in periodic systeme
Reactivity:
1.Basicity – extrem basicity
2.Nucleophility
Theory of HSAB:
Arhenius, Bronstead
To show basicity a presence of acid is needed,
it is necessary interaction of two partners
mostly we are considering reactions in water
but
also a lot of reactions proceeds in non-aqueous medium, but also there one partner may be an acid
and the other a base

Organometallic compounds
RELATIVITY ACID vs. BASE
K1
B2
B1
K2
pKa2 = 50
pKa1 = 25
Reactivity:
1.Basicity – extrem basicity
2.Nucleophility

Organometallic compounds
reactivity of organometal depends upon its position in periodic system
strong nucleophile
in case in the molecule is not acidic atom, then reacts as nucleophile
Reactivity:
1.Basicity – extrem basicity
2.Nucleophility

Organometallic compounds
reactivity of organometal depends upon its position in periodic system
depression of nucleophility by a tranfer to cuprates
Gilman reagent
Reactivity:
1.Basicity – extrem basicity
2.Nucleophility

Organometallic compounds
Methodes of preparation:
1.Reaction alkyl halogenides with metals
Grignard reagent
sometimes combined systemes
Reformatsky
ether

Organometallic compounds
this is imposible to use for organometals with Na and K
WURTZ
Mechanism:
2. exchange reaction between organometal and salt of other metal
M is more elektropozitive than  metal M1,  X is halogen

Organometallic compounds
3. application of acidic hydrogen atoms in a molecule