Build a Paper Model of Dengue Virus
This paper model of PDB entry 1k4r
shows the virus magnified by 1,500,000
times. The RNA genome, which
contains 10,649 nucleotides, can be
modeled using a piece of string
approximately 5.4 meters
long and placed inside
of the structure.
To learn about dengue
fever, see the National
Institute of Allergy and
Infectious Diseases’ site at
www.niaid.nih.gov/
topics/denguefever/
For more information
about dengue virus, see
the RCSB PDB’s Molecule
of the Month at
dx.doi.org/
10.2210/rcsb_pdb/
mom_2008_7
A+&
www.rcsb.org • info@rcsb.org
To build the dengue
virus, cut out the protein
structure below and fold
along the dotted lines.
Then tape or glue the
flaps into place to form
an icosahedron.
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This image was created from the experimentally-determined coordinates available in the PDB archive.
PDB ID: 1k4r: R.J. Kuhn, W. Zhang, M.G. Rossmann, S.V. Pletnev, J. Corver, E. Lenches, C.T. Jones, S. Mukhopadhyay, P.R. Chipman, E.G. Strauss, T.S. Baker, J.H. Strauss (2002)
Structure of dengue virus: implications for flavivirus organization, maturation, and fusion Cell 108:717-725
1k4r